Literature DB >> 28079202

Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor.

Yuhui Huang1, Mami Sumida1, Motofumi Kumazoe1, Kaori Sugihara1, Yumi Suemasu1, Shuhei Yamada1, Shuya Yamashita1, Jyunichi Miyakawa2, Takashi Takahashi3, Hiroshi Tanaka2, Yoshinori Fujimura1, Hirofumi Tachibana1.   

Abstract

Green tea polyphenol (-)-epigallocatechin-3-O-gallate (EGCG) has been attributed to the activation of its cell surface sensing receptor 67 kDa laminin receptor (67LR). However, the action of EGCG to activate 67LR remains unknown. Here we show that EGCG undergoes oligomer formation on its surface receptor 67LR.

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Year:  2017        PMID: 28079202     DOI: 10.1039/c6cc09504f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  5 in total

1.  Protective Effects of Epigallocatechin-3-Gallate from Green Tea in Various Kidney Diseases.

Authors:  Rattiyaporn Kanlaya; Visith Thongboonkerd
Journal:  Adv Nutr       Date:  2019-01-01       Impact factor: 8.701

Review 2.  Green Tea Catechins for Prostate Cancer Prevention: Present Achievements and Future Challenges.

Authors:  Valeria Naponelli; Ileana Ramazzina; Chiara Lenzi; Saverio Bettuzzi; Federica Rizzi
Journal:  Antioxidants (Basel)       Date:  2017-04-05

3.  "Cell-addictive" dual-target traceable nanodrug for Parkinson's disease treatment via flotillins pathway.

Authors:  YanHui Li; ZiXuan Chen; ZhiGuo Lu; QingHu Yang; LinYing Liu; ZhaoTan Jiang; LiQun Zhang; Xin Zhang; Hong Qing
Journal:  Theranostics       Date:  2018-10-29       Impact factor: 11.556

Review 4.  67-kDa Laminin Receptor-Mediated Cellular Sensing System of Green Tea Polyphenol EGCG and Functional Food Pairing.

Authors:  Yoshinori Fujimura; Motofumi Kumazoe; Hirofumi Tachibana
Journal:  Molecules       Date:  2022-08-11       Impact factor: 4.927

5.  Coptisine Induces Apoptosis in Human Hepatoma Cells Through Activating 67-kDa Laminin Receptor/cGMP Signaling.

Authors:  Li Zhou; Fan Yang; Guobing Li; Jingbin Huang; Yali Liu; Qian Zhang; Qin Tang; Changpeng Hu; Rong Zhang
Journal:  Front Pharmacol       Date:  2018-05-18       Impact factor: 5.810

  5 in total

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