Literature DB >> 2807717

Acquired immunity in rats against Angiostrongylus cantonensis infection.

L C Wang, D Chao, E R Chen.   

Abstract

Acquired immunity against Angiostrongylus cantonensis was induced by immunizing rats with somatic antigens from fifth-stage larvae and adult worms and live third-stage larvae. Rats immunized twice had significantly fewer worms than rats immunized three times. Fewer worms were recovered from rats immunized with 200 live third-stage larvae than from any other groups. Rats immunized with somatic antigens had higher enzyme-linked immunosorbent assay (ELISA) antibody levels than rats immunized with live larvae. Rats immunized with live third-stage larvae of Angiostrongylus cantonensis were more strongly protected against challenge infections (62-92%) than rats immunized with antigens extracted from fifth-stage larvae (0-30%) and adult worms (11-24%).

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Year:  1989        PMID： 2807717     DOI： 10.1016/0020-7519(89)90039-8

Source DB:  PubMed          Journal:  Int J Parasitol        ISSN： 0020-7519            Impact factor:   3.981


  7 in total

1.  Comparative studies on the proteomic expression patterns in the third- and fifth-stage larvae of Angiostrongylus cantonensis.

Authors:  Kuang-Yao Chen; Chien-Ju Cheng; Chuan-Min Yen; Petrus Tang; Lian-Chen Wang
Journal:  Parasitol Res       Date:  2014-07-16       Impact factor: 2.289

2.  Identification and characterization of an asparaginyl endopeptidase from Angiostrongylus cantonensis.

Authors:  Shih-Hsin Chang; Kuang-Yao Chen; Lian-Chen Wang
Journal:  Parasitol Res       Date:  2014-04-03       Impact factor: 2.289

3.  Activation of Sonic Hedgehog Leads to Survival Enhancement of Astrocytes via the GRP78-Dependent Pathway in Mice Infected with Angiostrongylus cantonensis.

Authors:  Kuang-Yao Chen; Chien-Ju Cheng; Lian-Chen Wang
Journal:  Biomed Res Int       Date:  2015-04-16       Impact factor: 3.411

4.  Transcriptome profiling of the fifth-stage larvae of Angiostrongylus cantonensis by next-generation sequencing.

Authors:  Lian-chen Wang; Kuang-yao Chen; Shih-hsin Chang; Li-yu Chung; Ruei-chi Richie Gan; Chien-ju Cheng; Petrus Tang
Journal:  Parasitol Res       Date:  2013-07-05       Impact factor: 2.289

5.  Anti-apoptotic effects of Sonic hedgehog signalling through oxidative stress reduction in astrocytes co-cultured with excretory-secretory products of larval Angiostrongylus cantonensis.

Authors:  Kuang-Yao Chen; Cheng-Hsun Chiu; Lian-Chen Wang
Journal:  Sci Rep       Date:  2017-02-07       Impact factor: 4.379

6.  Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.

Authors:  Kuang-Yao Chen; Yi-Ju Chen; Chien-Ju Cheng; Kai-Yuan Jhan; Lian-Chen Wang
Journal:  Parasit Vectors       Date:  2020-06-18       Impact factor: 3.876

7.  Identification and characterisation of microRNAs in young adults of Angiostrongylus cantonensis via a deep-sequencing approach.

Authors:  Shih-Hsin Chang; Petrus Tang; Cheng-Hung Lai; Ming-Ling Kuo; Lian-Chen Wang
Journal:  Mem Inst Oswaldo Cruz       Date:  2013-09       Impact factor: 2.743
  7 in total

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