Literature DB >> 28075069

Ebola Vaccination Using a DNA Vaccine Coated on PLGA-PLL/γPGA Nanoparticles Administered Using a Microneedle Patch.

Hung-Wei Yang1,2, Ling Ye3, Xin Dong Guo2,4, Chinglai Yang3, Richard W Compans3, Mark R Prausnitz2.   

Abstract

Ebola DNA vaccine is incorporated into PLGA-PLL/γPGA nanoparticles and administered to skin using a microneedle (MN) patch. The nanoparticle delivery system increases vaccine thermostability and immunogenicity compared to free vaccine. Vaccination by MN patch produces stronger immune responses than intramuscular administration.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Ebola DNA vaccine; cationic nanoparticles; indradermal vaccine delivery; microneedle patch; minimally invasive skin vaccination

Mesh：

Substances：

Year:  2016        PMID： 28075069     DOI： 10.1002/adhm.201600750

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  24 in total

Review 1.  Recent advances of controlled drug delivery using microfluidic platforms.

Authors:  Sharma T Sanjay; Wan Zhou; Maowei Dou; Hamed Tavakoli; Lei Ma; Feng Xu; XiuJun Li
Journal:  Adv Drug Deliv Rev       Date:  2017-09-15       Impact factor: 15.470

Review 2.  Potential of Microneedle Systems for COVID-19 Vaccination: Current Trends and Challenges.

Authors:  Jasmin Hassan; Charlotte Haigh; Tanvir Ahmed; Md Jasim Uddin; Diganta B Das
Journal:  Pharmaceutics       Date:  2022-05-16       Impact factor: 6.525

Review 3.  The potential role of using vaccine patches to induce immunity: platform and pathways to innovation and commercialization.

Authors:  Kamran Badizadegan; James L Goodson; Paul A Rota; Kimberly M Thompson
Journal:  Expert Rev Vaccines       Date:  2020-03-17       Impact factor: 5.217

Review 4.  Prophylactic vaccine delivery systems against epidemic infectious diseases.

Authors:  Chao Pan; Hua Yue; Li Zhu; Guang-Hui Ma; Heng-Liang Wang
Journal:  Adv Drug Deliv Rev       Date:  2021-07-17       Impact factor: 17.873

Review 5.  Emerging skin-targeted drug delivery strategies to engineer immunity: A focus on infectious diseases.

Authors:  Emrullah Korkmaz; Stephen C Balmert; Cara Donahue Carey; Geza Erdos; Louis D Falo
Journal:  Expert Opin Drug Deliv       Date:  2020-10-06       Impact factor: 8.129

6.  Self-Assembly DNA Polyplex Vaccine inside Dissolving Microneedles for High-Potency Intradermal Vaccination.

Authors:  Jing-Fong Liao; Jin-Ching Lee; Chun-Kuang Lin; Kuo-Chen Wei; Pin-Yuan Chen; Hung-Wei Yang
Journal:  Theranostics       Date:  2017-06-25       Impact factor: 11.556

Review 7.  Noninvasive vaccination against infectious diseases.

Authors:  Zhichao Zheng; Diana Diaz-Arévalo; Hongbing Guan; Mingtao Zeng
Journal:  Hum Vaccin Immunother       Date:  2018-05-17       Impact factor: 3.452

Review 8.  Nano-Microparticle Platforms in Developing Next-Generation Vaccines.

Authors:  Giuseppe Cappellano; Hugo Abreu; Chiara Casale; Umberto Dianzani; Annalisa Chiocchetti
Journal:  Vaccines (Basel)       Date:  2021-06-05

9.  Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge.

Authors:  Ying Liu; Ling Ye; Fang Lin; Yasmine Gomaa; David Flyer; Ricardo Carrion; Jean L Patterson; Mark R Prausnitz; Gale Smith; Gregory Glenn; Hua Wu; Richard W Compans; Chinglai Yang
Journal:  Sci Rep       Date:  2018-07-25       Impact factor: 4.379

10.  Skin vaccination with dissolvable microneedle patches incorporating influenza neuraminidase and flagellin protein nanoparticles induces broad immune protection against multiple influenza viruses.

Authors:  Ye Wang; Song Li; Chunhong Dong; Yao Ma; Yufeng Song; Wandi Zhu; Joo Kim; Lei Deng; Timothy L Denning; Sang-Moo Kang; Mark R Prausnitz; Bao-Zhong Wang
Journal:  ACS Appl Bio Mater       Date:  2021-05-11
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