Literature DB >> 2807493

Steroid induced glaucoma and cataract.

R Mohan, A R Muralidharan.   

Abstract

Long term use of topical & systemic steroids produce secondary open angle glaucoma similar to chronic simple glaucoma. The increased IOP caused by prolonged steroid therapy is reversible but the damage produced by it is irreversible. In this study, we analysed 25 patients (44 eyes) with steroid induced glaucoma, who reported to us with dimness of vision, haloes and elevated I.O.P. and were using steroids for long duration due to various causes. The behaviour of the I.O.P. due to different steroid preparations, the type of lenticular change, and the management of those cases are discussed in this paper. From our study we conclude that dexamethasone and betamethasone both topical as well as systemic are more potent in producing glaucoma and cataract than medrysone and prednisolone. The condition is reversible without permanent damage when the duration of steroid therapy is short and vice versa.

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Year:  1989        PMID: 2807493

Source DB:  PubMed          Journal:  Indian J Ophthalmol        ISSN: 0301-4738            Impact factor:   1.848


  13 in total

1.  Early and frequent development of ocular hypertension in children with nephrotic syndrome.

Authors:  Emi Kawaguchi; Kenji Ishikura; Riku Hamada; Yoshinobu Nagaoka; Yoshihiko Morikawa; Tomoyuki Sakai; Yuko Hamasaki; Hiroshi Hataya; Eiichiro Noda; Masaru Miura; Takashi Ando; Masataka Honda
Journal:  Pediatr Nephrol       Date:  2014-05-24       Impact factor: 3.714

2.  The risk benefit ratio of glucocorticoids in SLE: have things changed over the past 40 years?

Authors:  G Stojan; M Petri
Journal:  Curr Treatm Opt Rheumatol       Date:  2017-07-27

3.  Vehicle of triamcinolone acetonide is associated with retinal toxicity and transient increase of lens density.

Authors:  Wang Kai; Jiang Yanrong; Li Xiaoxin
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-02-02       Impact factor: 3.117

4.  Specific activation of the glucocorticoid receptor and modulation of signal transduction pathways in human lens epithelial cells.

Authors:  Vanita Gupta; Niranjan Awasthi; B J Wagner
Journal:  Invest Ophthalmol Vis Sci       Date:  2007-04       Impact factor: 4.799

Review 5.  Under pressure: an ocular complication of oral corticosteroid therapy.

Authors:  Lucy Anne Fitzgerald; Jan Dudley; Carol Inward; Jane Tizard
Journal:  BMJ Case Rep       Date:  2012-09-11

6.  Steroid dependent and independent ocular findings in Iranian children with nephrotic syndrome.

Authors:  Alaleh Gheissari; Hossein Attarzadeh; Hoda Sharif; Meraj Pourhossein; Alireza Merrikhi
Journal:  Int J Prev Med       Date:  2011-10

Review 7.  Etiopathogenesis of cataract: an appraisal.

Authors:  Varun B Gupta; Manjusha Rajagopala; Basavaiah Ravishankar
Journal:  Indian J Ophthalmol       Date:  2014-02       Impact factor: 1.848

8.  Antiallergic effect of an aqueous leaf extract of Pistia stratiotes in murine model of ovalbumin-induced allergic conjunctivitis.

Authors:  Samuel Abokyi; George Asumeng Koffuor; Samuel Kyei; Emmanuel A Asiamah; Clement Nsobire Atobiga; Agnes Awuah
Journal:  Pharmacognosy Res       Date:  2014-10

9.  Dexamethasone PLGA Microspheres for Sub-Tenon Administration: Influence of Sterilization and Tolerance Studies.

Authors:  Deyanira Barbosa-Alfaro; Vanessa Andrés-Guerrero; Ivan Fernandez-Bueno; María Teresa García-Gutiérrez; Esther Gil-Alegre; Irene Teresa Molina-Martínez; José Carlos Pastor-Jimeno; Rocío Herrero-Vanrell; Irene Bravo-Osuna
Journal:  Pharmaceutics       Date:  2021-02-06       Impact factor: 6.321

10.  Intraocular pressure variation in patients on long-term corticosteroids.

Authors:  John Shekhar Raju Mandapati; Arun Kumar Metta
Journal:  Indian Dermatol Online J       Date:  2011-07
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