| Literature DB >> 28074294 |
Abstract
Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used in patients with deep vein thrombosis (DVT), pulmonary embolism (PE) and atrial fibrillation (AF). However, there is insufficient data concerning the periinterventional, perioperative, and intensive care management of patients on NOACs. Therefore, the recommendations regarding this management rely on pharmacokinetics of the particular NOAC in combination with the individual patient's characteristics, bleeding risk of the planned intervention/surgery, and urgency of the procedure. This review summarizes evidence and recommendations regarding the optimal periinterventional/perioperative antithrombotic management of patients on NOACs.Entities:
Keywords: Anticoagulants; Bleeding; Intensive care; Perioperative care; Pharmacokinetics
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Year: 2017 PMID: 28074294 DOI: 10.1007/s00063-016-0239-8
Source DB: PubMed Journal: Med Klin Intensivmed Notfmed ISSN: 2193-6218 Impact factor: 0.840