Literature DB >> 28073859

Experimental Therapies for Ebola Virus Disease: What Have We Learned?

Frederick G Hayden1, Martin Friede2, Daniel G Bausch2.   

Abstract

Entities:  

Keywords:  Ebola; antivirals; clinical research; immunotherapeutics

Mesh：

Year:  2017        PMID： 28073859      PMCID： PMC5853886          DOI： 10.1093/infdis/jiw496

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


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  28 in total

1.  Design of a Randomized Controlled Trial for Ebola Virus Disease Medical Countermeasures: PREVAIL II, the Ebola MCM Study.

Authors:  Lori E Dodd; Michael A Proschan; Jacqueline Neuhaus; Joseph S Koopmeiners; James Neaton; John D Beigel; Kevin Barrett; Henry Clifford Lane; Richard T Davey
Journal:  J Infect Dis       Date:  2016-02-11       Impact factor: 5.226

2.  Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: a case-series of health-care workers.

Authors:  Michael Jacobs; Emma Aarons; Sanjay Bhagani; Ruaridh Buchanan; Ian Cropley; Susan Hopkins; Rebecca Lester; Daniel Martin; Neal Marshall; Stephen Mepham; Simon Warren; Alison Rodger
Journal:  Lancet Infect Dis       Date:  2015-08-25       Impact factor: 25.071

3.  Effect of Artesunate-Amodiaquine on Mortality Related to Ebola Virus Disease.

Authors:  Etienne Gignoux; Andrew S Azman; Martin de Smet; Philippe Azuma; Moses Massaquoi; Dorian Job; Amanda Tiffany; Roberta Petrucci; Esther Sterk; Julien Potet; Motoi Suzuki; Andreas Kurth; Angela Cannas; Anne Bocquin; Thomas Strecker; Christopher Logue; Thomas Pottage; Constanze Yue; Jean-Clement Cabrol; Micaela Serafini; Iza Ciglenecki
Journal:  N Engl J Med       Date:  2016-01-07       Impact factor: 91.245

4.  Ebola hemorrhagic fever: evaluation of passive immunotherapy in nonhuman primates.

Authors:  Peter B Jahrling; Joan B Geisbert; James R Swearengen; Thomas Larsen; Thomas W Geisbert
Journal:  J Infect Dis       Date:  2007-11-15       Impact factor: 5.226

5.  Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial.

Authors:  Ana Maria Henao-Restrepo; Ira M Longini; Matthias Egger; Natalie E Dean; W John Edmunds; Anton Camacho; Miles W Carroll; Moussa Doumbia; Bertrand Draguez; Sophie Duraffour; Godwin Enwere; Rebecca Grais; Stephan Gunther; Stefanie Hossmann; Mandy Kader Kondé; Souleymane Kone; Eeva Kuisma; Myron M Levine; Sema Mandal; Gunnstein Norheim; Ximena Riveros; Aboubacar Soumah; Sven Trelle; Andrea S Vicari; Conall H Watson; Sakoba Kéïta; Marie Paule Kieny; John-Arne Røttingen
Journal:  Lancet       Date:  2015-08-03       Impact factor: 79.321

6.  Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome.

Authors:  Jonathan S Towner; Pierre E Rollin; Daniel G Bausch; Anthony Sanchez; Sharon M Crary; Martin Vincent; William F Lee; Christina F Spiropoulou; Thomas G Ksiazek; Mathew Lukwiya; Felix Kaducu; Robert Downing; Stuart T Nichol
Journal:  J Virol       Date:  2004-04       Impact factor: 5.103

7.  State-of-the-Art Workshops on Medical Countermeasures Potentially Available for Human Use Following Accidental Exposures to Ebola Virus.

Authors:  Peter B Jahrling; Lisa E Hensley; Kevin Barrett; Henry Clifford Lane; Richard T Davey
Journal:  J Infect Dis       Date:  2015-05-09       Impact factor: 5.226

8.  Evaluating clinical trial designs for investigational treatments of Ebola virus disease.

Authors:  Ben S Cooper; Maciej F Boni; Wirichada Pan-ngum; Nicholas P J Day; Peter W Horby; Piero Olliaro; Trudie Lang; Nicholas J White; Lisa J White; John Whitehead
Journal:  PLoS Med       Date:  2015-04-14       Impact factor: 11.069

9.  First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease.

Authors:  Jenny Dörnemann; Chiara Burzio; Axelle Ronsse; Armand Sprecher; Hilde De Clerck; Michel Van Herp; Marie-Claire Kolié; Vesselina Yosifiva; Severine Caluwaerts; Anita K McElroy; Annick Antierens
Journal:  J Infect Dis       Date:  2017-01-15       Impact factor: 5.226

10.  Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea.

Authors:  Daouda Sissoko; Cedric Laouenan; Elin Folkesson; Abdoul-Bing M'Lebing; Abdoul-Habib Beavogui; Sylvain Baize; Alseny-Modet Camara; Piet Maes; Susan Shepherd; Christine Danel; Sara Carazo; Mamoudou N Conde; Jean-Luc Gala; Géraldine Colin; Hélène Savini; Joseph Akoi Bore; Frederic Le Marcis; Fara Raymond Koundouno; Frédéric Petitjean; Marie-Claire Lamah; Sandra Diederich; Alexis Tounkara; Geertrui Poelart; Emmanuel Berbain; Jean-Michel Dindart; Sophie Duraffour; Annabelle Lefevre; Tamba Leno; Olivier Peyrouset; Léonid Irenge; N'Famara Bangoura; Romain Palich; Julia Hinzmann; Annette Kraus; Thierno Sadou Barry; Sakoba Berette; André Bongono; Mohamed Seto Camara; Valérie Chanfreau Munoz; Lanciné Doumbouya; Patient Mumbere Kighoma; Fara Roger Koundouno; Cécé Moriba Loua; Vincent Massala; Kinda Moumouni; Célia Provost; Nenefing Samake; Conde Sekou; Abdoulaye Soumah; Isabelle Arnould; Michel Saa Komano; Lina Gustin; Carlotta Berutto; Diarra Camara; Fodé Saydou Camara; Joliene Colpaert; Léontine Delamou; Lena Jansson; Etienne Kourouma; Maurice Loua; Kristian Malme; Emma Manfrin; André Maomou; Adele Milinouno; Sien Ombelet; Aboubacar Youla Sidiboun; Isabelle Verreckt; Pauline Yombouno; Anne Bocquin; Caroline Carbonnelle; Thierry Carmoi; Pierre Frange; Stéphane Mely; Vinh-Kim Nguyen; Delphine Pannetier; Anne-Marie Taburet; Jean-Marc Treluyer; Jacques Kolie; Raoul Moh; Minerva Cervantes Gonzalez; Eeva Kuisma; Britta Liedigk; Didier Ngabo; Martin Rudolf; Ruth Thom; Romy Kerber; Martin Gabriel; Antonino Di Caro; Roman Wölfel; Jamal Badir; Mostafa Bentahir; Yann Deccache; Catherine Dumont; Jean-François Durant; Karim El Bakkouri; Marie Gasasira Uwamahoro; Benjamin Smits; Nora Toufik; Stéphane Van Cauwenberghe; Khaled Ezzedine; Eric D'Ortenzio; Eric Dortenzio; Louis Pizarro; Aurélie Etienne; Jérémie Guedj; Alexandra Fizet; Eric Barte de Sainte Fare; Bernadette Murgue; Tuan Tran-Minh; Christophe Rapp; Pascal Piguet; Marc Poncin; Bertrand Draguez; Thierry Allaford Duverger; Solenne Barbe; Guillaume Baret; Isabelle Defourny; Miles Carroll; Hervé Raoul; Augustin Augier; Serge P Eholie; Yazdan Yazdanpanah; Claire Levy-Marchal; Annick Antierrens; Michel Van Herp; Stephan Günther; Xavier de Lamballerie; Sakoba Keïta; France Mentre; Xavier Anglaret; Denis Malvy
Journal:  PLoS Med       Date:  2016-03-01       Impact factor: 11.069
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  12 in total

Review 1.  An update on ocular complications of Ebola virus disease.

Authors:  Jessica G Shantha; Ian Crozier; Steven Yeh
Journal:  Curr Opin Ophthalmol       Date:  2017-11       Impact factor: 3.761

Review 2.  Current status of small molecule drug development for Ebola virus and other filoviruses.

Authors:  Megan R Edwards; Christopher F Basler
Journal:  Curr Opin Virol       Date:  2019-04-16       Impact factor: 7.090

3.  Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.

Authors:  Priya Luthra; Jacinth Naidoo; Colette A Pietzsch; Sampriti De; Sudip Khadka; Manu Anantpadma; Caroline G Williams; Megan R Edwards; Robert A Davey; Alexander Bukreyev; Joseph M Ready; Christopher F Basler
Journal:  Antiviral Res       Date:  2018-08-23       Impact factor: 5.970

4.  Calcium Ions Directly Interact with the Ebola Virus Fusion Peptide To Promote Structure-Function Changes That Enhance Infection.

Authors:  Lakshmi Nathan; Alex L Lai; Jean Kaoru Millet; Marco R Straus; Jack H Freed; Gary R Whittaker; Susan Daniel
Journal:  ACS Infect Dis       Date:  2019-12-10       Impact factor: 5.084

5.  Clinician-initiated research on treating the host response to pandemic influenza.

Authors:  David S Fedson
Journal:  Hum Vaccin Immunother       Date:  2017-10-31       Impact factor: 3.452

6.  Quantification of Viral and Host Biomarkers in the Liver of Rhesus Macaques: A Longitudinal Study of Zaire Ebolavirus Strain Kikwit (EBOV/Kik).

Authors:  Alexandra Greenberg; Bertrand R Huber; David X Liu; James P Logue; Amanda M W Hischak; Randy J Hart; Maureen Abbott; Nejra Isic; Yohei M Hisada; Nigel Mackman; Richard S Bennett; Lisa E Hensley; John H Connor; Nicholas A Crossland
Journal:  Am J Pathol       Date:  2020-04-08       Impact factor: 4.307

7.  Inhibition of Ebola Virus by a Molecularly Engineered Banana Lectin.

Authors:  Evelyn M Covés-Datson; Julie Dyall; Lisa Evans DeWald; Steven R King; Derek Dube; Maureen Legendre; Elizabeth Nelson; Kelly C Drews; Robin Gross; Dawn M Gerhardt; Lisa Torzewski; Elena Postnikova; Janie Y Liang; Bhupal Ban; Jagathpala Shetty; Lisa E Hensley; Peter B Jahrling; Gene G Olinger; Judith M White; David M Markovitz
Journal:  PLoS Negl Trop Dis       Date:  2019-07-29

8.  Ocular complications in Ebola virus disease survivors: the importance of continuing care in West Africa.

Authors:  Duncan E Berry; Alexa L Li; Steven Yeh; Jessica G Shantha
Journal:  Expert Rev Ophthalmol       Date:  2019-06-04

9.  Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing.

Authors:  Punya Shrivastava-Ranjan; Mike Flint; Éric Bergeron; Anita K McElroy; Payel Chatterjee; César G Albariño; Stuart T Nichol; Christina F Spiropoulou
Journal:  MBio       Date:  2018-05-01       Impact factor: 7.867

Review 10.  Advances in Designing and Developing Vaccines, Drugs, and Therapies to Counter Ebola Virus.

Authors:  Kuldeep Dhama; Kumaragurubaran Karthik; Rekha Khandia; Sandip Chakraborty; Ashok Munjal; Shyma K Latheef; Deepak Kumar; Muthannan Andavar Ramakrishnan; Yashpal Singh Malik; Rajendra Singh; Satya Veer Singh Malik; Raj Kumar Singh; Wanpen Chaicumpa
Journal:  Front Immunol       Date:  2018-08-10       Impact factor: 7.561
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