Literature DB >> 28073679

Identification of early neurodegenerative change in presymptomatic spinocerebellar ataxia type 1: A diffusion tensor imaging study.

Yeon Ji Yoo1, Jeehae Oh2.   

Abstract

We report a 41-year-old man of presymptomatic spinocerebellar ataxia type 1. Diffusion tensor imaging (DTI) verified decreased fractional anisotropy of cerebellar afferent and efferent pathways compared to 5 age-matched healthy controls while conventional MRI revealed normal brain. DTI was valuable in detection of early microstructural damage of cerebellar pathways.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Diffusion tensor imaging; Spinocerebellar ataxia

Mesh：

Year:  2017        PMID： 28073679     DOI： 10.1016/j.parkreldis.2016.12.031

Source DB:  PubMed          Journal:  Parkinsonism Relat Disord        ISSN： 1353-8020            Impact factor:   4.891


  4 in total

Review 1.  Spinocerebellar ataxias: prospects and challenges for therapy development.

Authors:  Tetsuo Ashizawa; Gülin Öz; Henry L Paulson
Journal:  Nat Rev Neurol       Date:  2018-10       Impact factor: 42.937

2.  Microstructural Alterations in Asymptomatic and Symptomatic Patients with Spinocerebellar Ataxia Type 3: A Tract-Based Spatial Statistics Study.

Authors:  Xinwei Wu; Xinxin Liao; Yafeng Zhan; Cheng Cheng; Wei Shen; Mufang Huang; Zhifan Zhou; Zheng Wang; Zilong Qiu; Wu Xing; Weihua Liao; Beisha Tang; Lu Shen
Journal:  Front Neurol       Date:  2017-12-22       Impact factor: 4.003

3.  Autosomal dominant cerebellar ataxias: Imaging biomarkers with high effect sizes.

Authors:  Isaac M Adanyeguh; Vincent Perlbarg; Pierre-Gilles Henry; Daisy Rinaldi; Elodie Petit; Romain Valabregue; Alexis Brice; Alexandra Durr; Fanny Mochel
Journal:  Neuroimage Clin       Date:  2018-06-14       Impact factor: 4.881

4.  Spinocerebellar Ataxia Type 1: One-Year Longitudinal Study to Identify Clinical and MRI Measures of Disease Progression in Patients and Presymptomatic Carriers.

Authors:  Anna Nigri; Lidia Sarro; Alessia Mongelli; Anna Castaldo; Luca Porcu; Chiara Pinardi; Marina Grisoli; Stefania Ferraro; Laura Canafoglia; Elisa Visani; Maria Grazia Bruzzone; Lorenzo Nanetti; Franco Taroni; Caterina Mariotti
Journal:  Cerebellum       Date:  2021-06-09       Impact factor: 3.847
  4 in total

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