| Literature DB >> 28073000 |
Abstract
The nervous system is emerging as a regulator of malignancy. In this issue of Cancer Cell, Hayakawa et al. demonstrate a feedforward signaling loop in which tumor-derived nerve growth factor promotes enteric tumor innervation, and recruited nerves drive cancer growth through acetylcholine-regulated Wnt signaling and stimulation of further NGF release.Entities:
Mesh:
Year: 2017 PMID: 28073000 DOI: 10.1016/j.ccell.2016.12.008
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743