Hsiao-Han Lin1, Li-Min Huang, Suh-Chin Wu. 1. 1Doctoral Candidate, Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan 2MD, PhD, Distinguished Professor, Department of Pediatrics, College of Medicine, National Taiwan University & Director, Department of Pediatrics, National Taiwan University, Children's Hospital, Taipei, Taiwan 3PhD, Professor, Institute of Biotechnology Department of Medical Science, National Tsing Hua University, Hsinchu, Taiwan.