| Literature DB >> 28071900 |
Junjun Feng1, Xin Li1,2, Jin-Pei Cheng1,2.
Abstract
An efficient asymmetric vinylogous Michael addition of 3-alkylidene oxindoles and enals has been achieved using a chiral TBS-protected diphenylprolinol catalyst. The γ-substituted alkylidene oxindoles obtained bear a chiral tertiary center and are afforded in moderate to good yields and good to excellent enantioselectivities.Entities:
Year: 2017 PMID： 28071900 DOI： 10.1021/acs.joc.6b02582
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354