Literature DB >> 28070694

Early Evaluation and Monitoring of Critical Patients with Acute Respiratory Distress Syndrome (ARDS) Using Specific Genetic Polymorphisms.

Florin G Horhat1, Fuat Gundogdu2, Laurentiu V David1, Eugen S Boia1, Laurentiu Pirtea1, Razvan Horhat1, Alexandru Cucui-Cozma1, Ioana Ciuca1, Mircea Diaconu1, Razvan Nitu1, Monica Licker1, Delia I Horhat1, Alexandru F Rogobete3,4, Marius L Moise1, Calin Tataru5.   

Abstract

A high percentage of critical patients are found to develop acute respiratory distress syndrome (ARDS). Several studies have reported high mortality rates in these cases which are most frequently associated with multiple organ dysfunctions syndrome. Lately, many efforts have been made to evaluate and monitor ARDS in critical patients. In this regard, the assessment of genetic polymorphisms responsible for developing ARDS present as a challenge and are considered future biomarkers. Early detection of the specific polymorphic gene responsible for ARDS in critically ill patients can prove to be a useful tool in the future, able to help decrease the mortality rates in these cases. Moreover, identifying the genetic polymorphism in these patients can help in the implementation of a personalized intensive therapy scheme for every type of patient, based on its genotype.

Entities:  

Keywords:  Acute respiratory distress syndrome; Critically ill patients; Polymorphisms; Sepsis

Mesh:

Substances:

Year:  2017        PMID: 28070694     DOI: 10.1007/s10528-016-9787-0

Source DB:  PubMed          Journal:  Biochem Genet        ISSN: 0006-2928            Impact factor:   1.890


  6 in total

Review 1.  Biomarkers for the acute respiratory distress syndrome: how to make the diagnosis more precise.

Authors:  M Isabel García-Laorden; José A Lorente; Carlos Flores; Arthur S Slutsky; Jesús Villar
Journal:  Ann Transl Med       Date:  2017-07

2.  Association of HLA-DPA1 polymorphism with prolonged mechanical ventilation in patients undergoing liver transplantation.

Authors:  Eun Jung Kim; Min-Soo Kim; Myoung Soo Kim; Junhyun Nam; Seung Ho Choi
Journal:  Korean J Anesthesiol       Date:  2022-05-03

3.  A new method for identifying the acute respiratory distress syndrome disease based on noninvasive physiological parameters.

Authors:  Pengcheng Yang; Taihu Wu; Ming Yu; Feng Chen; Chunchen Wang; Jing Yuan; Jiameng Xu; Guang Zhang
Journal:  PLoS One       Date:  2020-02-05       Impact factor: 3.240

Review 4.  Cannabis Sativa Revisited-Crosstalk between microRNA Expression, Inflammation, Oxidative Stress, and Endocannabinoid Response System in Critically Ill Patients with Sepsis.

Authors:  Anca Raluca Dinu; Alexandru Florin Rogobete; Tiberiu Bratu; Sonia Elena Popovici; Ovidiu Horea Bedreag; Marius Papurica; Lavinia Melania Bratu; Dorel Sandesc
Journal:  Cells       Date:  2020-01-28       Impact factor: 6.600

Review 5.  Assessment of Metabolic and Nutritional Imbalance in Mechanically Ventilated Multiple Trauma Patients: From Molecular to Clinical Outcomes.

Authors:  Alexandru Florin Rogobete; Ioana Marina Grintescu; Tiberiu Bratu; Ovidiu Horea Bedreag; Marius Papurica; Zorin Petrisor Crainiceanu; Sonia Elena Popovici; Dorel Sandesc
Journal:  Diagnostics (Basel)       Date:  2019-11-01

6.  Impact of General Anesthesia Guided by State Entropy (SE) and Response Entropy (RE) on Perioperative Stability in Elective Laparoscopic Cholecystectomy Patients-A Prospective Observational Randomized Monocentric Study.

Authors:  Anca Raluca Dinu; Alexandru Florin Rogobete; Sonia Elena Popovici; Ovidiu Horea Bedreag; Marius Papurica; Corina Maria Dumbuleu; Raluca Ramona Velovan; Daiana Toma; Corina Maria Georgescu; Lavinia Ioana Trache; Claudiu Barsac; Loredana Luca; Bettina Buzzi; Andra Maghiar; Mihai Alexandru Sandesc; Samir Rimawi; Madalin Marian Vaduva; Lavinia Melania Bratu; Paul Manuel Luminosu; Dorel Sandesc
Journal:  Entropy (Basel)       Date:  2020-03-19       Impact factor: 2.524

  6 in total

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