Wolfgang M Kuebler1. 1. Institute of Physiology, Charité - Universitaetsmedizin Berlin, Charité - platz 1, 10117 Berlin, Germany; The Keenan Research Centre for Biomedical Science at St. Michael's, 30 Bond Street, M5B 1W8, Toronto, Ontario, Canada; Department of Surgery, University of Toronto, 149 College Street, Toronto, Ontario M5T 1P5, Canada; and Department of Physiology, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada wolfgang.kuebler@charite.de.