Literature DB >> 2806917

Nucleotide sequence of HIV1-NDK: a highly cytopathic strain of the human immunodeficiency virus.

B Spire1, J Sire, V Zachar, F Rey, F Barré-Sinoussi, F Galibert, A Hampe, J C Chermann.   

Abstract

A highly cytopathic strain of HIV1, named HIV1-NDK, has been isolated from a Zaïrian patient affected with AIDS. This isolate is 10(4) times more cytopathic and infectious than the prototype. To correlate the high cytopathic properties of this strain with genetic variations, we have cloned and sequenced the genome of this isolate. The principal feature which could be drawn from the fine analysis of the HIV1-NDK sequence is that the variability is not clustered in one particular region but rather spread out all along the genome. Only minor differences seem to be responsible for the acute biological effect of HIV1-NDK.

Entities:  

Mesh：

Year:  1989        PMID： 2806917     DOI： 10.1016/0378-1119(89)90188-1

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  45 in total

1.  Cooperation of the V1/V2 and V3 domains of human immunodeficiency virus type 1 gp120 for interaction with the CXCR4 receptor.

Authors:  B Labrosse; C Treboute; A Brelot; M Alizon
Journal:  J Virol       Date:  2001-06       Impact factor: 5.103

2.  Resistance to a drug blocking human immunodeficiency virus type 1 entry (RPR103611) is conferred by mutations in gp41.

Authors:  B Labrosse; O Pleskoff; N Sol; C Jones; Y Hénin; M Alizon
Journal:  J Virol       Date:  1997-11       Impact factor: 5.103

3.  Structural variability of env and gag gene products from a highly cytopathic strain of HIV-1.

Authors:  N Yahi; J Fantini; I Hirsch; J C Chermann
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

4.  RANTES and MCP-3 inhibit the replication of T-cell-tropic human immunodeficiency virus type 1 strains (SF-2, MN, and HE).

Authors:  D Schols; P Proost; J Van Damme; E De Clercq
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

5.  Phenotypically Vif- human immunodeficiency virus type 1 is produced by chronically infected restrictive cells.

Authors:  M Bouyac; F Rey; M Nascimbeni; M Courcoul; J Sire; D Blanc; F Clavel; R Vigne; B Spire
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

6.  Native but not denatured recombinant human immunodeficiency virus type 1 gp120 generates broad-spectrum neutralizing antibodies in baboons.

Authors:  N L Haigwood; P L Nara; E Brooks; G A Van Nest; G Ott; K W Higgins; N Dunlop; C J Scandella; J W Eichberg; K S Steimer
Journal:  J Virol       Date:  1992-01       Impact factor: 5.103

7.  Fast analysis of genomic homologies: primate immunodeficiency virus.

Authors:  M L Moncany; P R Courtois
Journal:  J Mol Evol       Date:  1996-08       Impact factor: 2.395

8.  Potent and highly selective human immunodeficiency virus type 1 (HIV-1) inhibition by a series of alpha-anilinophenylacetamide derivatives targeted at HIV-1 reverse transcriptase.

Authors:  R Pauwels; K Andries; Z Debyser; P Van Daele; D Schols; P Stoffels; K De Vreese; R Woestenborghs; A M Vandamme; C G Janssen
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205

9.  A comprehensive panel of near-full-length clones and reference sequences for non-subtype B isolates of human immunodeficiency virus type 1.

Authors:  F Gao; D L Robertson; C D Carruthers; S G Morrison; B Jian; Y Chen; F Barré-Sinoussi; M Girard; A Srinivasan; A G Abimiku; G M Shaw; P M Sharp; B H Hahn
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103

10.  The human immunodeficiency virus (HIV) gag gene product p18 is responsible for enhanced fusogenicity and host range tropism of the highly cytopathic HIV-1-NDK strain.

Authors:  J de Mareuil; B Brichacek; D Salaun; J C Chermann; I Hirsch
Journal:  J Virol       Date:  1992-11       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.