| Literature DB >> 28067423 |
Viola Lara Vogt1, Marja Äikiä2,3, Antonio Del Barrio4, Paul Boon5, Csaba Borbély6, Ema Bran7,8, Kees Braun9, Evelien Carette5, Maria Clark10, Judith Helen Cross10, Petia Dimova11, Daniel Fabo6, Nikolaos Foroglou12, Stefano Francione13, Anna Gersamia14,15, Antonio Gil-Nagel4, Alla Guekht14,15, Sue Harrison10, Hrvoje Hecimovic16, Einar Heminghyt17, Edouard Hirsch18, Alena Javurkova19, Reetta Kälviäinen3, Nicole Kavan20, Anna Kelemen6, Vasilios K Kimiskidis12, Margarita Kirschner21, Catherine Kleitz18, Teia Kobulashvili21, Mary H Kosmidis12, Selin Yagci Kurtish22, Mathieu Lesourd23, Sofia Ljunggren24, Morten Ingvar Lossius17, Kristina Malmgren24, Ruta Mameniskiené25,26, Patricia Martin-Sanfilippo10, Petr Marusic19, Marijke Miatton5, Çiğdem Özkara22, Federica Pelle13, Guido Rubboli27,28, Sarah Rudebeck10, Philippe Ryvlin23,28, Monique van Schooneveld29, Elisabeth Schmid21, Pia-Magdalena Schmidt1, Margitta Seeck20, Bernhard J Steinhoff30, Sara Shavel-Jessop10, Oana Tarta-Arsene7,8, Eugen Trinka21, Gerd Viggedal31, Anne-Sophie Wendling30, Juri-Alexander Witt1, Christoph Helmstaedter1.
Abstract
We explored the current practice with respect to the neuropsychological assessment of surgical epilepsy patients in European epilepsy centers, with the aim of harmonizing and establishing common standards. Twenty-six epilepsy centers and members of "E-PILEPSY" (a European pilot network of reference centers in refractory epilepsy and epilepsy surgery), were asked to report the status of neuropsychological assessment in adults and children via two different surveys. There was a consensus among these centers regarding the role of neuropsychology in the presurgical workup. Strong agreement was found on indications (localization, epileptic dysfunctions, adverse drugs effects, and postoperative monitoring) and the domains to be evaluated (memory, attention, executive functions, language, visuospatial skills, intelligence, depression, anxiety, and quality of life). Although 186 different tests are in use throughout these European centers, a core group of tests reflecting a moderate level of agreement could be discerned. Variability exists with regard to indications, protocols, and paradigms for the assessment of hemispheric language dominance. For the tests in use, little published evidence of clinical validity in epilepsy was provided. Participants in the survey reported a need for improvement concerning the validity of the tests, tools for the assessment of everyday functioning and accelerated forgetting, national norms, and test co-normalization. Based on the present survey, we documented a consensus regarding the indications and principles of neuropsychological testing. Despite the variety of tests in use, the survey indicated that there may be a core set of tests chosen based on experience, as well as on published evidence. By combining these findings with the results of an ongoing systematic literature review, we aim for a battery that can be recommended for the use across epilepsy surgical centers in Europe. Wiley Periodicals, Inc.Entities:
Keywords: Consensus; Diagnostic; Epilepsy surgery; Europe; Neuropsychology
Mesh：
Year: 2017 PMID： 28067423 DOI： 10.1111/epi.13646
Source DB: PubMed Journal: Epilepsia ISSN： 0013-9580 Impact factor: 5.864