| Literature DB >> 28066985 |
Kai Wang1, Xi Wang1, Chengsheng Han2, Wenda Hou1, Jinyang Wang1, Liangyi Chen2, Ying Luo1.
Abstract
A microwell-patterned membranous scaffold that integrates nano- and microscale topographical characteristics based on polyurethane is fabricated for transplanting syngeneic islets and allogeneic mesenchymal stem cells into diabetic rodents. The scaffold effectively allows for assembling of single cells/microtissues, enables the transplantation of cells with spatial control, and improves the transplant's engraftment efficacy in vivo for treating diabetes.Entities:
Keywords: diabetes; islets; mesenchymal stem cells; microwells; nanofibers
Mesh:
Year: 2016 PMID: 28066985 DOI: 10.1002/adma.201604600
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849