Literature DB >> 28066635

Rac1 is a potential target to circumvent radioresistance.

Wen-Ling Wang1, Wei-Chien Huang2.   

Abstract

Entities:  

Year:  2016        PMID: 28066635      PMCID: PMC5179424          DOI: 10.21037/jtd.2016.11.79

Source DB:  PubMed          Journal:  J Thorac Dis        ISSN: 2072-1439            Impact factor:   2.895


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  20 in total

1.  An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis.

Authors:  G Zhu; Z Fan; M Ding; H Zhang; L Mu; Y Ding; Y Zhang; B Jia; L Chen; Z Chang; W Wu
Journal:  Oncogene       Date:  2015-03-09       Impact factor: 9.867

2.  Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.

Authors:  Maria Soledad Sosa; Cynthia Lopez-Haber; Chengfeng Yang; Hongbin Wang; Mark A Lemmon; John M Busillo; Jiansong Luo; Jeffrey L Benovic; Andres Klein-Szanto; Hiroshi Yagi; J Silvio Gutkind; Ramon E Parsons; Marcelo G Kazanietz
Journal:  Mol Cell       Date:  2010-12-22       Impact factor: 17.970

3.  The role of radiotherapy-resistant stem cells in breast cancer recurrence.

Authors:  Cheikh Menaa; Jian Jian Li
Journal:  Breast Cancer Manag       Date:  2013

4.  Heregulin beta1 promotes breast cancer cell proliferation through Rac/ERK-dependent induction of cyclin D1 and p21Cip1.

Authors:  Chengfeng Yang; Eric A Klein; Richard K Assoian; Marcelo G Kazanietz
Journal:  Biochem J       Date:  2008-02-15       Impact factor: 3.857

Review 5.  Role of Rho GTPases and their regulators in cancer progression.

Authors:  Rajamani Rathinam; Allison Berrier; Suresh K Alahari
Journal:  Front Biosci (Landmark Ed)       Date:  2011-06-01

6.  Rac1-regulated endothelial radiation response stimulates extravasation and metastasis that can be blocked by HMG-CoA reductase inhibitors.

Authors:  Melanie Hamalukic; Johannes Huelsenbeck; Arno Schad; Stefan Wirtz; Bernd Kaina; Gerhard Fritz
Journal:  PLoS One       Date:  2011-10-19       Impact factor: 3.240

7.  Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells.

Authors:  Paige J Baugher; Lakshmi Krishnamoorthy; Janet E Price; Surangani F Dharmawardhane
Journal:  Breast Cancer Res       Date:  2005-09-30       Impact factor: 6.466

8.  Rac1 as a potential therapeutic target for chemo-radioresistant head and neck squamous cell carcinomas (HNSCC).

Authors:  S Skvortsov; J Dudás; P Eichberger; M Witsch-Baumgartner; J Loeffler-Ragg; C Pritz; V H Schartinger; H Maier; J Hall; P Debbage; H Riechelmann; P Lukas; I Skvortsova
Journal:  Br J Cancer       Date:  2014-05-01       Impact factor: 7.640

9.  Effect of combined irradiation and EGFR/Erb-B inhibition with BIBW 2992 on proliferation and tumour cure in cell lines and xenografts.

Authors:  Kristin Gurtner; Nadja Ebert; Dorothee Pfitzmann; Wolfgang Eicheler; Daniel Zips; Michael Baumann; Mechthild Krause
Journal:  Radiat Oncol       Date:  2014-12-02       Impact factor: 3.481

10.  RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment.

Authors:  A L Hein; C M Post; Y M Sheinin; I Lakshmanan; A Natarajan; C A Enke; S K Batra; M M Ouellette; Y Yan
Journal:  Oncogene       Date:  2016-05-16       Impact factor: 9.867

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