| Literature DB >> 2806472 |
S Dessí1, B Batetta, A Carrucciu, D Pulisci, S Laconi, A M Fadda, C Anchisi, P Pani.
Abstract
In the present study serum lipoproteins were investigated during cell proliferation induced by a potent mitogen, lead nitrate. A strong decrease in HDL2 and a concomitant increase in HDL3 were observed in lead-treated rats. The recovery of normal lipoprotein pattern took place together with the regression of hyperplastic process. Since a decrease in HDL also occurs under other conditions of cell growth, we hypothesize that a decrease in HDL, mainly in HDL2 subfraction, may represent a generalized phenomenon related to massive cell proliferation.Entities:
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Year: 1989 PMID： 2806472 DOI： 10.1016/0014-4800(89)90010-5
Source DB: PubMed Journal: Exp Mol Pathol ISSN： 0014-4800 Impact factor: 3.362