Literature DB >> 28063603

Prostate-specific Membrane Antigen-targeted Ligand Positron Emission Tomography/Computed Tomography and Immunohistochemical Findings in a Patient With Synchronous Metastatic Penile and Prostate Cancer.

Michael Froehner1, Friederike Kuithan2, Klaus Zöphel3, Ulrike Heberling4, Michael Laniado5, Manfred P Wirth4.   

Abstract

A 68-year-old man presented with synchronous metastatic penile and prostate cancer. 68Ga-labeled prostate-specific membrane antigen-targeted ligand positron emission tomography/computed tomography (PSMA-PET/CT) revealed tracer uptake in inguinal, pelvic, and retroperitoneal metastases. Lymph node biopsies and immunohistochemical staining revealed that both cancers involved the lymph nodes and expressed PSMA. In the deposits of penile squamous cell carcinoma, PSMA expression was seen in tumor vessels and may explain the PSMA-PET/CT positivity of inguinal nodes involved in squamous cell carcinoma. The interpretation of imaging in synchronous tumors should take this fact into consideration.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Year:  2017        PMID： 28063603     DOI： 10.1016/j.urology.2016.11.040

Source DB:  PubMed          Journal:  Urology        ISSN： 0090-4295            Impact factor:   2.649


  7 in total

1.  [68Ga]Ga-PSMA-11 in prostate cancer: a comprehensive review.

Authors:  Frédéric Bois; Camille Noirot; Sébastien Dietemann; Ismini C Mainta; Thomas Zilli; Valentina Garibotto; Martin A Walter
Journal:  Am J Nucl Med Mol Imaging       Date:  2020-12-15

Review 2.  Targeting PSMA by radioligands in non-prostate disease-current status and future perspectives.

Authors:  Philipp Backhaus; Benjamin Noto; Nemanja Avramovic; Lena Sophie Grubert; Sebastian Huss; Martin Bögemann; Lars Stegger; Matthias Weckesser; Michael Schäfers; Kambiz Rahbar
Journal:  Eur J Nucl Med Mol Imaging       Date:  2018-01-15       Impact factor: 9.236

Review 3.  Pearls and pitfalls in clinical interpretation of prostate-specific membrane antigen (PSMA)-targeted PET imaging.

Authors:  Sara Sheikhbahaei; Ali Afshar-Oromieh; Matthias Eiber; Lilja B Solnes; Mehrbod S Javadi; Ashley E Ross; Kenneth J Pienta; Mohamad E Allaf; Uwe Haberkorn; Martin G Pomper; Michael A Gorin; Steven P Rowe
Journal:  Eur J Nucl Med Mol Imaging       Date:  2017-08-01       Impact factor: 9.236

4.  68Ga-Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography: How Much Specific It Is?

Authors:  Manas Kumar Sahoo
Journal:  World J Nucl Med       Date:  2017 Oct-Dec

5.  Potential Receptors for Targeted Imaging of Lymph Node Metastases in Penile Cancer.

Authors:  Christa A M van der Fels; Selma Palthe; Henk Buikema; Marius C van den Heuvel; Annemarie Leliveld; Igle Jan de Jong
Journal:  Diagnostics (Basel)       Date:  2020-09-15

6.  An overview on prostate-specific membrane antigen uptake in malignancies other than prostate cancer: A pictorial essay.

Authors:  Esmail Jafari; Hojjat Ahmadzadehfar; Habibollah Dadgar; Majid Assadi
Journal:  World J Nucl Med       Date:  2020-07-22

7.  Nonspecific Uptake of 68Ga-Prostate-Specific Membrane Antigen in Diseases other than Prostate Malignancy on Positron Emission Tomography/Computed Tomography Imaging: A Pictorial Assay and Review of Literature.

Authors:  Dharmender Malik; Apurva Sood; Bhagwant Rai Mittal; Harmandeep Singh; Rajender Kumar Basher; Jaya Shukla; Anish Bhattacharya; Shrawan Kumar Singh
Journal:  Indian J Nucl Med       Date:  2018 Oct-Dec
  7 in total

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