Literature DB >> 28063009

DNA methylation signatures in circulating cell-free DNA as biomarkers for the early detection of cancer.

Junyun Wang1, Xiao Han1,2, Yingli Sun3.   

Abstract

Detecting cell-free DNA (cfDNA) or circulating tumor DNA (ctDNA) in plasma or serum could serve as a "liquid biopsy", which would be useful for numerous diagnostic applications. cfDNA methylation detection is one of the most promising approaches for cancer risk assessment. Here, we reviewed the literature related to the use of serum or plasma circulating cell-free DNA for cancer diagnosis in the early stage and their power as future biomarkers.

Entities:  

Keywords:  DNA methylation; cancer detection; circulating cell-free DNA; diagnostic markers

Mesh：

Substances：

Year:  2017        PMID： 28063009     DOI： 10.1007/s11427-016-0253-7

Source DB:  PubMed          Journal:  Sci China Life Sci        ISSN： 1674-7305            Impact factor:   6.038


  9 in total

1.  Integrative analysis identifies potential DNA methylation biomarkers for pan-cancer diagnosis and prognosis.

Authors:  Wubin Ding; Geng Chen; Tieliu Shi
Journal:  Epigenetics       Date:  2019-01-29       Impact factor: 4.528

2.  The Prognostic Value of Plasma Cell-Free DNA Concentration in the Prostate Cancer: A Systematic Review and Meta-Analysis.

Authors:  Hongtao Liu; Yuzhen Gao; Somayeh Vafaei; Xiao Gu; Xiaoli Zhong
Journal:  Front Oncol       Date:  2021-03-11       Impact factor: 6.244

Review 3.  Epigenetic inactivation of tumour suppressor coding and non-coding genes in human cancer: an update.

Authors:  Pere Llinàs-Arias; Manel Esteller
Journal:  Open Biol       Date:  2017-09       Impact factor: 6.411

4.  Epitranscriptomics: Toward A Better Understanding of RNA Modifications.

Authors:  Xushen Xiong; Chengqi Yi; Jinying Peng
Journal:  Genomics Proteomics Bioinformatics       Date:  2017-05-19       Impact factor: 7.691

5.  Plasma cell-free DNA methylation combined with tumor mutation detection in prognostic prediction of patients with non-small cell lung cancer (NSCLC).

Authors:  Dan Guo; Liang Yang; Jianwei Yang; Ke Shi
Journal:  Medicine (Baltimore)       Date:  2020-06-26       Impact factor: 1.817

Review 6.  Emerging non-invasive detection methodologies for lung cancer.

Authors:  Zhen Li; Jinian Shu; Bo Yang; Zuojian Zhang; Jingyun Huang; Yang Chen
Journal:  Oncol Lett       Date:  2020-03-12       Impact factor: 2.967

7.  Identification of diagnostic biomarkers in patients with gestational diabetes mellitus based on transcriptome gene expression and methylation correlation analysis.

Authors:  Enchun Li; Tengfei Luo; Yingjun Wang
Journal:  Reprod Biol Endocrinol       Date:  2019-12-27       Impact factor: 5.211

8.  Pan-Cancer DNA Methylation Analysis and Tumor Origin Identification of Carcinoma of Unknown Primary Site Based on Multi-Omics.

Authors:  Pengfei Liu
Journal:  Front Genet       Date:  2022-01-06       Impact factor: 4.599

9.  Identification of inflammation-related DNA methylation biomarkers in periodontitis patients based on weighted co-expression analysis.

Authors:  Pengcheng Wang; Bingbing Wang; Zheng Zhang; Zuomin Wang
Journal:  Aging (Albany NY)       Date:  2021-08-04       Impact factor: 5.682
  9 in total

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