Literature DB >> 28061350

Achieving Efficient Manufacturing and Quality Assurance through Synthetic Cell Therapy Design.

Yonatan Y Lipsitz1, Patrick Bedford2, Anthony H Davies3, Nicholas E Timmins4, Peter W Zandstra5.   

Abstract

New methods to manipulate gene and cell state can be used to engineer cell functionality, simplify quality assessment, and enhance manufacturability. These strategies could help overcome unresolved cell therapy manufacturing challenges and complement frameworks to design quality into these complex cellular systems, ultimately increasing patient access to living therapeutics.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28061350     DOI： 10.1016/j.stem.2016.12.003

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  8 in total

Review 1.  Manufacturing Cell Therapies Using Engineered Biomaterials.

Authors:  Amr A Abdeen; Krishanu Saha
Journal:  Trends Biotechnol       Date:  2017-07-12       Impact factor: 19.536

2.  Effect of Cryopreservation on Autologous Chimeric Antigen Receptor T Cell Characteristics.

Authors:  Sandhya R Panch; Sandeep K Srivastava; Nasha Elavia; Andrew McManus; Shutong Liu; Ping Jin; Steven L Highfill; Xiaobai Li; Pradeep Dagur; James N Kochenderfer; Terry J Fry; Crystal L Mackall; Daniel Lee; Nirali N Shah; David F Stroncek
Journal:  Mol Ther       Date:  2019-05-30       Impact factor: 11.454

3.  Perspectives on Manufacturing of High-Quality Cell Therapies.

Authors:  Isabelle Rivière; Krishnendu Roy
Journal:  Mol Ther       Date:  2017-04-24       Impact factor: 11.454

4.  Engineering Mammalian Cells to Control Glucose Homeostasis.

Authors:  Jiawei Shao; Xinyuan Qiu; Mingqi Xie
Journal:  Methods Mol Biol       Date:  2021

5.  Distinct carbon sources affect structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells.

Authors:  Cláudia Correia; Alexey Koshkin; Patrícia Duarte; Dongjian Hu; Ana Teixeira; Ibrahim Domian; Margarida Serra; Paula M Alves
Journal:  Sci Rep       Date:  2017-08-17       Impact factor: 4.379

Review 6.  Engineering precision therapies: lessons and motivations from the clinic.

Authors:  Mingqi Xie; Mirta Viviani; Martin Fussenegger
Journal:  Synth Biol (Oxf)       Date:  2020-11-24

7.  Modulating cell state to enhance suspension expansion of human pluripotent stem cells.

Authors:  Yonatan Y Lipsitz; Curtis Woodford; Ting Yin; Jacob H Hanna; Peter W Zandstra
Journal:  Proc Natl Acad Sci U S A       Date:  2018-06-04       Impact factor: 11.205

8.  Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice.

Authors:  Tobias Deuse; Grigol Tediashvili; Xiaomeng Hu; Alessia Gravina; Annika Tamenang; Dong Wang; Andrew Connolly; Christian Mueller; Beñat Mallavia; Mark R Looney; Malik Alawi; Lewis L Lanier; Sonja Schrepfer
Journal:  Proc Natl Acad Sci U S A       Date:  2021-07-13       Impact factor: 11.205
  8 in total

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