PURPOSE OF REVIEW: Zika virus (ZIKV) was not initially thought to be an important cause of neurologic disease, but with the recent epidemic in the Western Hemisphere, there is a growing body of evidence for possible neurologic complications. This review discusses these in addition to what is known about modes of transmission, testing for the virus, as well as future directions. RECENT FINDINGS: ZIKV disease has been associated with microcephaly and congenital eye disease in infants, as well as with Guillain-Barré syndrome, uveitis, myelitis, and meningoencephalitis in adults. SUMMARY: Even though most infections are asymptomatic, there are important possible neurologic complications of ZIKV disease in both children and adults of which neurologists should be aware.
PURPOSE OF REVIEW: Zika virus (ZIKV) was not initially thought to be an important cause of neurologic disease, but with the recent epidemic in the Western Hemisphere, there is a growing body of evidence for possible neurologic complications. This review discusses these in addition to what is known about modes of transmission, testing for the virus, as well as future directions. RECENT FINDINGS:ZIKV disease has been associated with microcephaly and congenital eye disease in infants, as well as with Guillain-Barré syndrome, uveitis, myelitis, and meningoencephalitis in adults. SUMMARY: Even though most infections are asymptomatic, there are important possible neurologic complications of ZIKV disease in both children and adults of which neurologists should be aware.
Authors: Patrícia Brasil; Patricia Carvalho Sequeira; Andrea D'Avila Freitas; Heruza Einsfeld Zogbi; Guilherme Amaral Calvet; Rogerio Valls de Souza; André Machado Siqueira; Marcos Cesar Lima de Mendonca; Rita Maria Ribeiro Nogueira; Ana Maria Bispo de Filippis; Tom Solomon Journal: Lancet Date: 2016-04-02 Impact factor: 79.321
Authors: Emilio Dirlikov; Kyle R Ryff; Jomil Torres-Aponte; Dana L Thomas; Janice Perez-Padilla; Jorge Munoz-Jordan; Elba V Caraballo; Myriam Garcia; Marangely Olivero Segarra; Graciela Malave; Regina M Simeone; Carrie K Shapiro-Mendoza; Lourdes Romero Reyes; Francisco Alvarado-Ramy; Angela F Harris; Aidsa Rivera; Chelsea G Major; Marrielle Mayshack; Luisa I Alvarado; Audrey Lenhart; Miguel Valencia-Prado; Steve Waterman; Tyler M Sharp; Brenda Rivera-Garcia Journal: MMWR Morb Mortal Wkly Rep Date: 2016-05-06 Impact factor: 17.586
Authors: Matthew J Kuehnert; Sridhar V Basavaraju; Robin R Moseley; Lisa L Pate; Susan A Galel; Phillip C Williamson; Michael P Busch; Jose O Alsina; Consuelo Climent-Peris; Peter W Marks; Jay S Epstein; Hira L Nakhasi; J Peyton Hobson; David A Leiby; Pradip N Akolkar; Lyle R Petersen; Brenda Rivera-Garcia Journal: MMWR Morb Mortal Wkly Rep Date: 2016-06-24 Impact factor: 17.586
Authors: D Trew Deckard; Wendy M Chung; John T Brooks; Jessica C Smith; Senait Woldai; Morgan Hennessey; Natalie Kwit; Paul Mead Journal: MMWR Morb Mortal Wkly Rep Date: 2016-04-15 Impact factor: 17.586