M V Jali1, Sanjay Kambar2, Sujata M Jali3, Nandita Pawar4, Prachi Nalawade4. 1. KLES Diabetes Centre, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belagavi, 590010, India. Electronic address: drmvjali@gmail.com. 2. KLES Diabetes Centre, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belagavi, 590010, India; Department of Community Medicine, KLE University's J. N. Medical College, Belagavi, 590010, India. 3. KLES Diabetes Centre, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belagavi, 590010, India; Department of Paediatrics, KLE University's J. N. Medical College, Belagavi, 590010, India. 4. KLES Diabetes Centre, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belagavi, 590010, India.
Abstract
AIMS: To determine the prevalence of Thyroid dysfunction among Type 2 Diabetes mellitus. METHODOLOGY: A cross-sectional hospital-based study is conducted to find out the prevalence of thyroid dysfunction. 713 type 2 diabetes mellitus (T2DM) subjects were enrolled in the survey. These subjects were investigated for fasting blood sugar (FBS), glycosylated haemoglobin (HbA1c), total triiodothyronine (T3), total thyroxine (T4), and thyroid-stimulating hormone (TSH). RESULTS: Prevalence of thyroid dysfunction in T2DM was found in 16.2%. Gender-specific prevalence found higher in females (25%) compared to males (10.1%) (P<0.001). Age-specific prevalence found higher in the age group ≥50 yrs. (19%) Compared to other age groups (P=0.036). Subjects with poor glycaemic control demonstrated higher prevalence (27.9%) (P=0.012). Subjects with long-standing T2DM had an increased risk for thyroid dysfunction (19.8%) though findings were not statistically significant. (P=0.42). CONCLUSION: The prevalence of thyroid dysfunction with T2DM (16.2%) was high in females compared to males and especially hypothyroidism being more typical. Failure to recognise the presence of thyroid dysfunction among T2DM patients may be a primary cause of poor management of diabetes. We recommend universal screening and regular monitoring of thyroid dysfunction in T2DM patients.
AIMS: To determine the prevalence of Thyroid dysfunction among Type 2 Diabetes mellitus. METHODOLOGY: A cross-sectional hospital-based study is conducted to find out the prevalence of thyroid dysfunction. 713 type 2 diabetes mellitus (T2DM) subjects were enrolled in the survey. These subjects were investigated for fasting blood sugar (FBS), glycosylated haemoglobin (HbA1c), total triiodothyronine (T3), total thyroxine (T4), and thyroid-stimulating hormone (TSH). RESULTS: Prevalence of thyroid dysfunction in T2DM was found in 16.2%. Gender-specific prevalence found higher in females (25%) compared to males (10.1%) (P<0.001). Age-specific prevalence found higher in the age group ≥50 yrs. (19%) Compared to other age groups (P=0.036). Subjects with poor glycaemic control demonstrated higher prevalence (27.9%) (P=0.012). Subjects with long-standing T2DM had an increased risk for thyroid dysfunction (19.8%) though findings were not statistically significant. (P=0.42). CONCLUSION: The prevalence of thyroid dysfunction with T2DM (16.2%) was high in females compared to males and especially hypothyroidism being more typical. Failure to recognise the presence of thyroid dysfunction among T2DM patients may be a primary cause of poor management of diabetes. We recommend universal screening and regular monitoring of thyroid dysfunction in T2DM patients.
Authors: Adi H Khassawneh; Abdel-Hameed Al-Mistarehi; Anas M Zein Alaabdin; Laith Khasawneh; Thekraiat M AlQuran; Khalid A Kheirallah; Nesreen A Saadeh; Othman Beni Yonis; Mohamid Shawkat; Nail Obeidat Journal: Int J Gen Med Date: 2020-10-12