Literature DB >> 28057482

Distinguishing between expert and statistical systems for application under ICH M7.

Chris Barber1, Thierry Hanser2, Philip Judson3, Richard Williams4.   

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Year:  2017        PMID: 28057482     DOI: 10.1016/j.yrtph.2016.12.012

Source DB:  PubMed          Journal:  Regul Toxicol Pharmacol        ISSN: 0273-2300            Impact factor:   3.271


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  6 in total

1.  Use of Lhasa Limited Products for the In Silico Prediction of Drug Toxicity.

Authors:  David J Ponting; Michael J Burns; Robert S Foster; Rachel Hemingway; Grace Kocks; Donna S MacMillan; Andrew L Shannon-Little; Rachael E Tennant; Jessica R Tidmarsh; David J Yeo
Journal:  Methods Mol Biol       Date:  2022

Review 2.  In silico toxicology: From structure-activity relationships towards deep learning and adverse outcome pathways.

Authors:  Jennifer Hemmerich; Gerhard F Ecker
Journal:  Wiley Interdiscip Rev Comput Mol Sci       Date:  2020-03-31

3.  Quantitative Determination of Four Potential Genotoxic Impurities in the Active Pharmaceutical Ingredients in TSD-1 Using UPLC-MS/MS.

Authors:  Taiyu Wang; Hailong Yang; Jie Yang; Ningjie Guo; Guodong Wu; Xueyu Xu; Ming An
Journal:  Molecules       Date:  2022-06-27       Impact factor: 4.927

4.  Use of transcriptomics in hazard identification and next generation risk assessment: A case study with clothianidin.

Authors:  Heike Sprenger; Katrin Kreuzer; Jimmy Alarcan; Kristin Herrmann; Julia Buchmüller; Philip Marx-Stoelting; Albert Braeuning
Journal:  Food Chem Toxicol       Date:  2022-06-08       Impact factor: 5.572

5.  Management of pharmaceutical ICH M7 (Q)SAR predictions - The impact of model updates.

Authors:  Catrin Hasselgren; Joel Bercu; Alex Cayley; Kevin Cross; Susanne Glowienke; Naomi Kruhlak; Wolfgang Muster; John Nicolette; M Vijayaraj Reddy; Roustem Saiakhov; Krista Dobo
Journal:  Regul Toxicol Pharmacol       Date:  2020-10-13       Impact factor: 3.271

6.  Discovery of new acetylcholinesterase inhibitors for Alzheimer's disease: virtual screening and in vitro characterisation.

Authors:  Benoit David; Pascal Schneider; Philipp Schäfer; Jörg Pietruszka; Holger Gohlke
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051

  6 in total

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