Michele Iovino , Vito Angelo Giagulli , Brunella Licchelli , Emanuela Iovino , Edoardo Guastamacchia , Vincenzo Triggiani 1 . Show Affiliations »
Abstract
BACKGROUND: Magnocellular neurosecretory neurons of the hypothalamic supraoptic (SON) and paraventricular (PVN) nuclei synthesize vasopressin and oxytocin in response to signals generated by osmoreceptors and baroreceptors and, respectively, by receptors of the nipples and cervix. METHODS: We analyzed the literature identifying relevant articles dealing with synaptic inputs of neural afferent pathways to Vasopressin-and Oxytocin-secreting neurons of SON and PVN. RESULTS: This article focuses on the multisynaptic pathways involved in the regulation of Vasopressin and Oxytocin secretion. CONCLUSION: An updated topographic description of the afferent pathways involved in the regulation of VPergic and OTergic neurons and their synaptic inputs inducing the stimulus-secretion-coupling has been depicted. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
BACKGROUND: Magnocellular neurosecretory neurons of the hypothalamic supraoptic (SON) and paraventricular (PVN) nuclei synthesize vasopressin and oxytocin in response to signals generated by osmoreceptors and baroreceptors and, respectively, by receptors of the nipples and cervix. METHODS: We analyzed the literature identifying relevant articles dealing with synaptic inputs of neural afferent pathways to Vasopressin -and Oxytocin-secreting neurons of SON and PVN. RESULTS: This article focuses on the multisynaptic pathways involved in the regulation of Vasopressin and Oxytocin secretion. CONCLUSION: An updated topographic description of the afferent pathways involved in the regulation of VPergic and OTergic neurons and their synaptic inputs inducing the stimulus-secretion-coupling has been depicted. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
Entities: Gene
Keywords:
Circumventricular organs; forebrain and brainstem afferent pathways; nucleus tracti solitarii; oxytocin; supraopticzzm321990and paraventricular magnocellular neurons; synaptic inputs; vasopressin.
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Year: 2016
PMID: 28056741 DOI: 10.2174/1871530317666170104124229
Source DB: PubMed Journal: Endocr Metab Immune Disord Drug Targets ISSN: 1871-5303 Impact factor: 2.895