Literature DB >> 28054564

CFTR structure: lassoing cystic fibrosis.

Bob Ford1.   

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Year:  2017        PMID： 28054564     DOI： 10.1038/nsmb.3353

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


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  8 in total

1.  Allosteric modulation balances thermodynamic stability and restores function of ΔF508 CFTR.

Authors:  Andrei A Aleksandrov; Pradeep Kota; Liying Cui; Tim Jensen; Alexey E Alekseev; Santiago Reyes; Lihua He; Martina Gentzsch; Luba A Aleksandrov; Nikolay V Dokholyan; John R Riordan
Journal:  J Mol Biol       Date:  2012-03-08       Impact factor: 5.469

2.  Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

Authors:  J R Riordan; J M Rommens; B Kerem; N Alon; R Rozmahel; Z Grzelczak; J Zielenski; S Lok; N Plavsic; J L Chou
Journal:  Science       Date:  1989-09-08       Impact factor: 47.728

3.  Syntaxin 16 binds to cystic fibrosis transmembrane conductance regulator and regulates its membrane trafficking in epithelial cells.

Authors:  Heon Yung Gee; Bor Luen Tang; Kyung Hwan Kim; Min Goo Lee
Journal:  J Biol Chem       Date:  2010-09-08       Impact factor: 5.157

4.  Atomic Structure of the Cystic Fibrosis Transmembrane Conductance Regulator.

Authors:  Zhe Zhang; Jue Chen
Journal:  Cell       Date:  2016-12-01       Impact factor: 41.582

5.  Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions.

Authors:  Zoltan Bozoky; Mickael Krzeminski; Ranjith Muhandiram; James R Birtley; Ateeq Al-Zahrani; Philip J Thomas; Raymond A Frizzell; Robert C Ford; Julie D Forman-Kay
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-04       Impact factor: 11.205

6.  Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770.

Authors:  Fredrick Van Goor; Sabine Hadida; Peter D J Grootenhuis; Bill Burton; Dong Cao; Tim Neuberger; Amanda Turnbull; Ashvani Singh; John Joubran; Anna Hazlewood; Jinglan Zhou; Jason McCartney; Vijayalaksmi Arumugam; Caroline Decker; Jennifer Yang; Chris Young; Eric R Olson; Jeffery J Wine; Raymond A Frizzell; Melissa Ashlock; Paul Negulescu
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-21       Impact factor: 11.205

Review 7.  Structure and function of the CFTR chloride channel.

Authors:  D N Sheppard; M J Welsh
Journal:  Physiol Rev       Date:  1999-01       Impact factor: 37.312

8.  Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner.

Authors:  Paul D W Eckford; Canhui Li; Mohabir Ramjeesingh; Christine E Bear
Journal:  J Biol Chem       Date:  2012-08-31       Impact factor: 5.157
  8 in total
  3 in total

Review 1.  Ion channels of the lung and their role in disease pathogenesis.

Authors:  Rafal Bartoszewski; Sadis Matalon; James F Collawn
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2017-10-12       Impact factor: 5.464

Review 2.  Multidrug Resistance in Mammals and Fungi-From MDR to PDR: A Rocky Road from Atomic Structures to Transport Mechanisms.

Authors:  Narakorn Khunweeraphong; Karl Kuchler
Journal:  Int J Mol Sci       Date:  2021-04-30       Impact factor: 5.923

Review 3.  Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives.

Authors:  Irene Brusa; Elvira Sondo; Federico Falchi; Nicoletta Pedemonte; Marinella Roberti; Andrea Cavalli
Journal:  J Med Chem       Date:  2022-04-04       Impact factor: 8.039
  3 in total

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