Literature DB >> 28053730

Multiple sclerosis following a spinal cord injury: a rare and unfortunate case.

R S Salinas-González1, L Rodríguez-Sánchez2, R A Pelayo-Vergara3, J Benito-Penalva4.   

Abstract

This is a case report and review of literature with the objective report of the case of a young man with physical disability following a traumatic spinal cord injury (SCI) who was later newly diagnosed with multiple sclerosis (MS) in an inpatient SCI rehabilitation center. (Barcelona, Spain). A 24-year-old male sustained a traumatic spinal cord lesion (T9 AIS A) as the result of a motorcycle accident. He completed his rehabilitation process without complications and returned to the community having adjusted to his new disability. Two and a half years after his initial injury, he attended the clinic after experiencing 2 months of paresthesias in his left hand, progressing to his right upper limb, and difficulty with fine hand movements. An magnetic resonance imaging (MRI) was arranged and although post-traumatic syringomyelia was ruled out, demyelinating areas in the cervical spinal cord were found. A brain MRI revealed multiple demyelinating lesions suggestive of MS. The diagnosis of MS was confirmed by a neurologist and treatment was started with daily doses of glatiramer acetate. At this time the patient was still independent in transfers, activities of daily living and wheelchair management. In young patients with SCI, adequate follow-up is important to detect subsequent complications that may lead to clinical and functional deterioration with a view to uncommon causes such as MS.

Entities:  

Keywords:  Multiple sclerosis; Neurological manifestations; Spinal cord diseases

Year:  2016        PMID: 28053730      PMCID: PMC5125067          DOI: 10.1038/scsandc.2015.27

Source DB:  PubMed          Journal:  Spinal Cord Ser Cases        ISSN: 2058-6124


  5 in total

1.  The relationship of MS to physical trauma and psychological stress: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.

Authors:  D S Goodin; G C Ebers; K P Johnson; M Rodriguez; W A Sibley; J S Wolinsky
Journal:  Neurology       Date:  1999-06-10       Impact factor: 9.910

2.  Increased risk of multiple sclerosis after traumatic brain injury: a nationwide population-based study.

Authors:  Jiunn-Horng Kang; Herng-Ching Lin
Journal:  J Neurotrauma       Date:  2011-12-23       Impact factor: 5.269

Review 3.  Multiple sclerosis: diagnosis and the management of acute relapses.

Authors:  S M Leary; B Porter; A J Thompson
Journal:  Postgrad Med J       Date:  2005-05       Impact factor: 2.401

4.  Risk of multiple sclerosis after head injury: record linkage study.

Authors:  M J Goldacre; J D Abisgold; D G R Yeates; V Seagroatt
Journal:  J Neurol Neurosurg Psychiatry       Date:  2006-03       Impact factor: 10.154

Review 5.  Physical trauma and risk of multiple sclerosis: a systematic review and meta-analysis of observational studies.

Authors:  Carole A Lunny; Shawn N Fraser; Jennifer A Knopp-Sihota
Journal:  J Neurol Sci       Date:  2013-08-15       Impact factor: 3.181

  5 in total

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