Literature DB >> 28050451

Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis.

Sujata Siwatch1, Vanita Suri2, Pooja Sikka3, Neelam Aggarwal4, Seema Chopra3.   

Abstract

Choriocarcinoma presents usually as persistent trophoblastic disease, with prognosis worsening with duration from antecedent pregnancy. We present a unique case of a woman with choriocarcinoma who presented in the third trimester of pregnancy with eclampsia. She was managed with magnesium sulphate and underwent a caesarean section. However, she developed seizures in the post-partum period that were further investigated and attributed to intracranial metastatic lesions of Gestational Trophoblastic Neoplasia (GTN). We discussed the diagnostic challenge in this rare case of GTN and the grave potential it can have in such a presentation, as in our patient.

Entities:  

Keywords:  Eclampsia; Gestational trophoblastic disease; Magnesium sulphate

Year:  2016        PMID: 28050451      PMCID: PMC5198404          DOI: 10.7860/JCDR/2016/19344.8769

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  10 in total

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Journal:  Gynecol Oncol       Date:  1995-11       Impact factor: 5.482

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Journal:  Cancer       Date:  1983-11-01       Impact factor: 6.860

Review 9.  Diagnosis and management of atypical preeclampsia-eclampsia.

Authors:  Baha M Sibai; Caroline L Stella
Journal:  Am J Obstet Gynecol       Date:  2008-11-18       Impact factor: 8.661

10.  Choriocarcinoma brain metastasis in a patient with viable intrauterine pregnancy. Case report.

Authors:  Adam N Mamelak; Gregory J Withers; Xuedong Wang
Journal:  J Neurosurg       Date:  2002-08       Impact factor: 5.115

  10 in total

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