Literature DB >> 28050416

A Rare Case of An Atypical Solitary Fibrous Tumour of Orbit.

Hetal Mahendra Mehta1, Avinash Babarao Ingole2, Anuja Mihir Gharat3, Sujit Mardansingh Murade4, Anjali Darius Nicholson5.   

Abstract

Solitary fibrous tumours are of mesenchymal origin and comprise of uncommon spindle cell neoplasias. Most commonly the lesions arise from pleura but other rarer sites include lungs, peritoneum, pericardium, nasal cavities, thyroid, parotid gland and orbit. We report the case of a 41-year-old male patient who presented to us with a painless, progressive growth of a mass in the superior part of left orbit with proptosis and inferotemporal displacement of the left eye. Computed Tomography (CT) scan revealed homogeneous enhancing lesion in the superior compartment of left orbit in the extraconal region, extending intraconally and distorting the globe. Upon imaging, the differential diagnosis were lacrimal gland tumour, atypical cavernous haemangioma and nerve sheath tumour. Surgical treatment included complete excision of the mass with the intraoperative finding of mass extending upto the superior oblique tendon, a part of which was excised. Histopathological examination revealed CD34 positive, Bcl-2 and MIC-2 positive tumour with the diagnosis of a solitary fibrous tumour with atypical features but no malignant features. After a follow-up of 18 months, no recurrence was detected.

Entities:  

Keywords:  Immunohistochemistry; Orbit; Spindle cell neoplasias

Year:  2016        PMID: 28050416      PMCID: PMC5198369          DOI: 10.7860/JCDR/2016/21001.8793

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  14 in total

1.  Solitary fibrous tumor of the orbit with intracranial involvement.

Authors:  Thomas K Young; Thomas G Hardy
Journal:  Ophthalmic Plast Reconstr Surg       Date:  2011 May-Jun       Impact factor: 1.746

2.  Orbital solitary fibrous tumor: encompassing terminology for hemangiopericytoma, giant cell angiofibroma, and fibrous histiocytoma of the orbit: reappraisal of 41 cases.

Authors:  Emiko Furusato; Ives A Valenzuela; Julie C Fanburg-Smith; Aaron Auerbach; Bungo Furusato; J Douglas Cameron; Elisabeth J Rushing
Journal:  Hum Pathol       Date:  2010-11-05       Impact factor: 3.466

3.  Orbital hemangiopericytoma and solitary fibrous tumor: a morphologic continuum.

Authors:  J D Goldsmith; M van de Rijn; N Syed
Journal:  Int J Surg Pathol       Date:  2001-10       Impact factor: 1.271

Review 4.  Solitary fibrous tumor of the orbit: is it rare? Report of a case series and review of the literature.

Authors:  Francesco P Bernardini; Carlo de Conciliis; Susan Schneider; Robert C Kersten; Dwight R Kulwin
Journal:  Ophthalmology       Date:  2003-07       Impact factor: 12.079

5.  Atypical and malignant solitary fibrous tumors in extrathoracic locations: evidence of their comparability to intra-thoracic tumors.

Authors:  A V Vallat-Decouvelaere; S M Dry; C D Fletcher
Journal:  Am J Surg Pathol       Date:  1998-12       Impact factor: 6.394

6.  Solitary fibrous tumor of the orbit.

Authors:  D M Dorfman; K To; G R Dickersin; A E Rosenberg; B Z Pilch
Journal:  Am J Surg Pathol       Date:  1994-03       Impact factor: 6.394

7.  Expression of bcl-2 oncoprotein in benign and malignant spindle cell tumors of soft tissue, skin, serosal surfaces, and gastrointestinal tract.

Authors:  S Suster; C Fisher; C A Moran
Journal:  Am J Surg Pathol       Date:  1998-07       Impact factor: 6.394

8.  Solitary fibrous tumor. Consistent CD34 immunoreactivity and occurrence in the orbit.

Authors:  W H Westra; W L Gerald; J Rosai
Journal:  Am J Surg Pathol       Date:  1994-10       Impact factor: 6.394

9.  Orbital solitary fibrous tumor: A rare clinicopathologic correlation and review of literature.

Authors:  Mohammad Javed Ali; Santosh G Honavar; Milind N Naik; Geeta K Vemuganti
Journal:  J Res Med Sci       Date:  2013-06       Impact factor: 1.852

10.  Solitary fibrous tumor of the orbit.

Authors:  Sumiti Gupta; Renuka Verma; Rajeev Sen; Ishwar Singh; Nisha Marwah; Rachneet Kohli
Journal:  Asian J Neurosurg       Date:  2016 Jan-Mar
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  1 in total

1.  Solitary Fibrous Tumor of the Orbit: A Case Series With Clinicopathologic Correlation and Evaluation of STAT6 as a Diagnostic Marker.

Authors:  Nathan W Blessing; J Antonio Bermudez-Magner; Maria P Fernandez; Andrew E Rosenberg; Sander R Dubovy; Thomas E Johnson
Journal:  Ophthalmic Plast Reconstr Surg       Date:  2020 Mar/Apr       Impact factor: 2.011

  1 in total

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