| Literature DB >> 28050384 |
Alvin Jose Pothadiyil1, Suresh Bhat2, Fredrick Paul3, Jithesh Mampatta1, Mahesh Srinivas1.
Abstract
Inflammatory Myofibroblastic Tumour (IMT) or 'pseudotumour' of the kidney is a rare benign tumour of unknown aetiology affecting mostly young adults. A subset of IMT is neoplastic and harbours translocations of activin receptor-like kinase-1 (ALK-1) gene and can recur or rarely metastasize. Presentation varies from an incidentaloma to gross haematuria. Clinical examination and radiological investigations are usually inconclusive. Often, biopsy is inconclusive necessitating a management similar to that of Renal Cell Cancer (RCC). Diagnosis is based on immunohistochemistry. We are reporting a case of IMT in a 50-year-old male patient who presented with left flank mass which on evaluation was suggestive of left renal cell carcinoma. Excision of the tumour, histopathological examination and Immunohistochemistry proved the tumour to be IMT.Entities:
Keywords: Inflammation; Neoplasm; Nephrectomy; Pseudotumour
Year: 2016 PMID: 28050384 PMCID: PMC5198337 DOI: 10.7860/JCDR/2016/22465.8856
Source DB: PubMed Journal: J Clin Diagn Res ISSN: 0973-709X