Tinnitus in Elderly Individuals: Discomfort and Impact in the Quality of Life.

Introduction Tinnitus is a symptom that affects mainly the elderly and can negatively influence their quality of life. Objective The objective of our study is to evaluate the existence of a relationship between the quality of life and the impact caused by tinnitus in elderly individuals, considering the age and gender variables. Method We conducted a cross-sectional study in elderly people of both genders who participate in the extension activities at the university. The evaluation was composed of anamnesis and WHOQOL-OLD instruments, to evaluate the quality of life, and Tinnitus Handicap Inventory (THI) for the evaluation of the tinnitus impact. Result We evaluated 36 elderly individuals with an average age of 68.6 ± 6.8 years old, 72.2 % of them were women. We verified that most of the subjects classified their tinnitus as weak (44.4%) or medium (36.1%). The score average in the THI was 20 points, with predominant classification of tinnitus impact as negligible (41.7%) or mild (30.6%). In the WHOQOL-OLD, the average score was 15.6 ± 1.6 points (total score). The negative correlation between the THI score and the WHOQOL-OLD score was found in the sensory domain operation and total score. Conclusion The results obtained in the study prove that the quality of life of the elderly individuals evaluated is related to a discomfort caused by the tinnitus.

Introduction

Tinnitus is a frequent symptom in individuals of several age groups. Age increase, however, is one of the factors that determine its presence,1 and it is more common among the individuals from 40 years old on.2 A study reveals that there may be a relation between the presence of tinnitus and the hearing loss presented by the elderly.3

The prevalence among elderly individuals is variably described in the consulted literature. A Japanese study reported the presence of tinnitus in 11.9% of middle-aged adults and elderly people. A population survey performed in the United States showed that tinnitus was present in 14.4% of the middle-aged adults and elderly individuals.4 The influence of the gender variable on the presence of tinnitus is still controversial in the specialized literature.

While some national and international studies state that gender does not influence tinnitus,5 6 others highlight that it is more frequent in women1 or in men.4 7

Some research states that the tinnitus can cause stress and emotional alterations, interfering in the quality of life and even preventing individuals from having a life considered normal.2 7 8 Other studies, however, highlight that the impact of the tinnitus in the quality of life is highly variable. While some individuals say that the symptom does not cause any trouble in their daily activities, others say they are highly harmed.5 9 Thus, it is difficult to initially determine whether tinnitus will or will not have a negative impact in the quality of life. The presence of depression, anxiety, neuroticism, psychasthenia, and schizoid aspects may be indicators that the tinnitus impact will be higher,10 11 but there is still not enough scientific evidence that the use of antidepressants promotes improvement in tinnitus.12

The evaluation of tinnitus impact can be done in several ways. One of the most used instruments worldwide is the Tinnitus Handicap Inventory (THI), developed by Newman, Jacobson, and Spritzer.13 It has a version in Brazilian Portuguese.14 The instrument is composed of 25 questions that evaluate how tinnitus interferes in daily activities.

Quality of life can be measured through different methods, from the use of wide and qualitative questions to the use of closed questionnaires, allowing us to quantify different aspects of the variable. Because it is a widely impacting and important topic, it has been studied for some time by the World Health Organization (WHO) researchers. Based on several studies and with researchers from several countries, quality of life is defined as “the individual's perception of their life position within the context of culture systems and values in which they are inserted and related to their objectives, expectations, standards, and concerns.”15 From this definition, the researchers elaborated questionnaires to evaluate quality of life, initially broad and comprehensive and further reduced and applicable to specific populations, as the WHOQOL-OLD (World Health Organization Quality of Life - Older Adults), to be used specifically with the elderly.16

The application and the joint analysis of these two instruments can be useful in clinical practice, evaluation processes, diagnosis, and treatment of elderly with tinnitus, enabling a broad view of the individual, not limited to the specific aspect of the tinnitus. A search in the literature, however, showed that it is rare to find papers in which instruments to evaluate the quality of life and to evaluate tinnitus are used together,5 8 specially in Brazil, or instruments for the evaluation of quality of life developed specifically for the elderly.

Therefore, considering the lack of studies, the fact that Brazil has a significant and ever-increasing number of elderly individuals, and given the need to study the disorders presented by the population group with a focus on maintaining quality of life, we decided to carry out this study. Thus, the study aims to evaluate the relation between the quality of life and the impact caused by the tinnitus in elderly individuals, considering the age and gender variables.

Method

This is a study with a cross-sectional design. The sample was composed of elderly individuals of both genders, from 60 years old on, who had tinnitus. We selected the sample based on convenience. We considered all the seniors to be physically active because they would participate in extension projects in the institution, and they would practice physical exercises and other activities promoted by the projects (lectures and workshops).

The individuals included in the sample were elderly that reported tinnitus and were available to voluntarily participate in the research, signing a free and clarified consent term (TCLE), and filling out all questionnaires used for data collection. The individuals excluded were the ones with a history of psychiatric cognitive alterations.

Initially, we approached the elderly individuals at the university facilities and invited them to participate in the research. Those who accepted were led to a room where they signed the TCLE and were instructed on filling out of the questionnaires used in the research. Elderly with difficulties in reading and writing received help from a trained researcher previously, in order not to induce answers.

Initially, we carried out an anamnesis, aimed at obtaining sociodemographic data of the elderly. During the initial interview, the participants were questioned about their age, school level, marital status, and diseases. At this point, they were also invited to subjectively analyze the intensity of the tinnitus that they presented, classifying it as weak, medium, or strong. After that, everyone responded to the quality of life evaluation instrument of the World Health Organization, the WHOQOL-OLD, and the THI, to evaluate the impact of the tinnitus in their daily activities.

WHOQOL-OLD is an instrument developed by WHO, already translated and validated for Brazilian Portuguese,16 developed to be specifically applied to elderly individuals. The questionnaire is composed of 24 items that allow the evaluation of six parts or domains: operation of the sensory domain; past, present, and future activities; social participation; death and dying; and intimacy. It is also possible to evaluate the total score obtained in the instrument. For each one of the 24 questions, the individual must check one of the five alternatives presented. The higher the score obtained, the better the quality of life of the individual evaluated.

The impact of the tinnitus was evaluated by the THI instrument, also translated to and validated for Brazilian Portuguese.14 There are 25 questions that assess the influence of the tinnitus in daily situations. For each situation, the individual must check one of the three alternatives presented (yes — 4 points; sometimes — 2 points; no — 0 points). The total score varies from 0 to 100 points (or %), and the impact of the symptom can be considered negligible (0 to 16%), mild (18 to 36%), moderate (38 to 56%), severe (58 to 76%), or catastrophic (78 to 100%). Therefore, the higher the score, the higher the negative impact of the tinnitus in the life of the individual evaluated.

The data were analyzed statistically and in a descriptive quantitative manner. With the help of the software SPSS (Statistical Package for the Social Sciences), version 17.0, absolute and relative frequencies were calculated for the categorical variables and for the central tendency measures (mean and median) and variability (standard deviation, range and interquartile range) for the continuous variables, where for the latter the symmetry of distributions was checked by the Kolmogorov-Smirnov test.

The bivariate analysis between categorical variables was done by the Pearson Chi-square test and Fisher's exact test. In the comparison of the continuous variables between two independent groups, we used the t-Student and the Mann Whitney test. When comparing three or more independent groups, we used the Variance Analysis (One Way) – Post Hoc Tukey – or Kruskal Wallys – Post Hoc Dunn test. To evaluate the linearity relation between the continuous variables, the Pearson or Spearman correlation coefficients were used. For statistical decision criteria, we adopted a level of significance adopted (α) 5%.

The Ethics Research Committee of the institution evaluated and approved the study, under number 2008-125H.

Results

The sample consisted of 36 elderly individuals, mainly women (72.2%). The age average was 68.6 ± 6.8 years. Considering the age groups, there was greater concentration in the group aged 60 to 69 years, 63.9% (n = 23). Regarding school level, most individuals had gone to basic school (63.9%), 38.9% having not completed it and 25% having completed it. When instructed to subjectively classify the sensation of the tinnitus intensity, approximately half of the sample said it was weak (44.4%). The characterization of the sample is found on Table 1.

Table 1

Sample characterization

Variables	n = 36
Gender – n (%)
Female	26 (72.2)
Male	10 (27.8)
Age (years)
Average ± Standard Deviation	68.6 ± 6.8
Minimum - Maximum	60–83
Age group (years) – n (%)
60 to 69	23 (63.9)
70 to 79	9 (25.0)
More than 79	4 (11.1)
Education
Never studied	2 (5.6)
Incomplete primary education	14 (38.9)
Primary education	9 (25.0)
Incomplete high school	1 (2.8)
High School	6 (16.7)
Incomplete university	2 (5.6)
University	2 (5.6)

Regarding the score in the THI, this variable presented an asymmetric distribution, indicating that the estimates should occur as a function of the median and not of the mean. The median was 20 points.

As for the THI score classification, the largest part of the sample presented discomfort considered negligible and mild. The data are presented in Table 2.

Table 2

Absolute and relative distribution for the score and classification THI

Variables	n = 36
Scores THI £
Median (Q1-Q3 quartile)	20.0 (6.0–41.0)
Minimum - maximum	0–96
Classification THI – n(%)
Negligible (0–16%)	15 (41.7)
Mild (18–36%)	11 (30.6)
Moderate (38–56%)	7 (19.4)
Severe (58–76%)	1 (2.8)
Catastrophic (78–100%)	2 (5.6)

Abbreviation: THI, Tinnitus Handicap Inventory.

£: Variable with asymmetric distribution (KS; p > 0.200).

The analysis of the data between the THI score and the gender variable showed a significant difference (p<0.05), indicating that the scores for the men (median = 6.0 points) were smaller than for the women (median = 22.0 points) (Table 3). When the THI score was compared with the age and to the age group, the significant differences were not confirmed, indicating that the THI score does not depend on the age of the individuals evaluated.

Table 3

Mean and standard deviation of the THI scores according to gender and age group; and coefficient of correlation between the age and the score THI

Variables	Score THI	p
Gender – average ± SD (median)		0.041₱
Female	30.8 ± 26.8 (22.0)
Male	13.8 ± 18.9 (6.0)

Abbreviation: SD, standard deviation; THI, Tinnitus Handicap Inventory.

₱: Mann Whitney test.

The evaluation data of the quality of life, evaluated through the WHOQOL-OLD, have shown that the elderly present average scores that vary according to the domain evaluated and are presented on Table 4.

Table 4

Measures of central tendency and variability for scores of WHOQOL-OLD domains

WHOQOL-OLD	n = 36
Operation of the sensory
Average ± SD	14.2 ± 3.7
Minimum - Maximum	8–20
Autonomy
Average ± SD	15.1 ± 2.9
Minimum - Maximum	8–20
Past, present and future activities
Average ± SD	15.5 ± 2.3
Minimum - Maximum	10–20
Social participation
Average ± SD	15.5 ± 2.7
Minimum - Maximum	9–20
Death and dying
Average ± SD	14.9 ± 3.8
Minimum - Maximum	5–20
Intimacy
Average ± SD	15.6 ± 2.6
Minimum - Maximum	9–20
p (mean comparison between domains)	0.295ɛ
Total score
Average ± SD	15.1 ± 1.6
Minimum - Maximum	11.7–17.8

Abbreviation: SD, standard deviation; WHOQOL-OLD (World Health Organization Quality of Life -Older Adults.

ɛ: repeated measures analysis - Post Hoc test Bonferroni p – p value.

When the average of the domains was compared with each other, there were no significant differences (p > 0.05), indicating that the domains presented similar average scores. Therefore, although the averages of the domains have presented variations, they were expressive to the point of affirming that the quality of life in a certain domain is better than in the other.

The comparative analysis that involved the WHOQOL-OLD domain scores and the THI scores showed that there was a significant negative correlation of moderate degree (r = -0.516; p = 0.001) between the operation of the sensory domain and the THI, indicating that the higher the score in the domain, the smaller the THI score.

Another significant correlation was between the total score in the WHOQOL-OLD and the THI score (r = -0.395; p<0.05), where the total elevated scores in the WHOQOL-OLD were related to the low scores of the THI (or vice-versa). Therefore, the better the quality of life, the smaller the impact provoked by the tinnitus (Table 5).

Table 5

Correlation analysis between the scores on the WHOQOL-OLD and THI

WHOQOL-OLD	Correlation scores THI
	rŦ	p value
Operation of the sensory	−0.516	0.001**
Autonomy	−0.123	0.473
Past, present and future activities	0.042	0.809
Social participation	−0.118	0.492
Death and dying	−0.226	0.186
Intimacy	−0.186	0.277
Total score	−0.395	0.017*

Abbreviation: THI, Tinnitus Handicap Inventory; WHOQOL-OLD (World Health Organization Quality of Life -Older Adults.

₮: Pearson Coefficient of correlation.

The average scores of the WHOQOL-OLD domains were also compared to the classification in the THI. A significant difference was observed in the domain of the sensory operation (p = 0.001), where the individuals with tinnitus classified as negligible and mild presented higher scores than the individuals with tinnitus impact considered moderate and severe/catastrophic. There were also differences in the total score of WHOQOL-OLD, when again the averages in the THI classification rated negligible and mild showed significantly higher averages than the ones obtained by the individuals with moderate and severe/catastrophic THI classification (Table 6).

Table 6

Mean and standard deviation of the WHOQOL-OLD domains according to the classification THI

WHOQOL-OLD	Classification THI				pɸ
	Negligible (n = 15)	Mild (n = 11)	Moderate (n = 7)	Severe or catastrophic (n = 3)
Operation of the sensory	14.7 ± 3.1a	16.6 ± 2.6a	11.1 ± 3.6b	10.0 ± 2.0b	0.001*
Autonomy	15.4 ± 1.8	15.4 ± 3.6	14.1 ± 3.6	14.0 ± 3.6	0.695
Past, present and future activities	15.7 ± 2.0	15.5 ± 2.8	14.3 ± 2.5	17.0 ± 1.0	0.362
Social participation	15.8 ± 2.2	15.7 ± 3.2	14.3 ± 3.1	16.0 ± 2.6	0.646
Death and dying	16.1 ± 3.7	14.8 ± 4.5	13.7 ± 3.5	13.0 ± 2.6	0.450
Intimacy	15.9 ± 2.5	16.2 ± 2.1	14.8 ± 3.2	13.6 ± 3.2	0.408
Total score	15.6 ± 1.2a	15.7 ± 1.8a	13.7 ± 1.3b	13.9 ± 1.2b	0.016*

Abbreviation: THI, Tinnitus Handicap Inventory; WHOQOL-OLD (World Health Organization Quality of Life -Older Adults.

ɸ: Kruskal Wallys test – Post Hoc teste de Dunn, which means followed by the same letter do not differ significantly.

Discussion

The data obtained show that in the group of elderly evaluated, women had a predominant participation. This fact may be due to the place where the research was conducted. A study showed the massive participation of women in community groups,17 18 with an average age and age group similar to the elderly researched.19 The low education level of the participants is similar to the other national research and is a predominant characteristic in the country, and are taken into consideration when planning activities and programs for this age group.19

The THI score was similar to the study mentioned previously, where part of the sample was also composed of elderly that practice physical activities,20

but inferior to other studies that evaluated adult and elderly individuals with tinnitus.2 21 Physical activity is beneficial to the individuals evaluated. A research highlighted that the practice of physical activities is a determining factor for a lesser negative impact of the tinnitus among the elderly, possibly because it promotes the wellbeing and diminishes the discomfort sensation.20

In the analysis of THI classification, a higher number of individuals with impact considered negligible and mild corroborates other national studies,22 but differs from others 2 23 24 that observed a greater number of individuals with negligible, mild and moderate discomfort. As in our study sample was composed of adult and elderly individuals, it is believed that this data can be taken into consideration, once the elderly can be more resilient, being able to adapt faster to unfavorable situations.25

When we analyzed the score obtained in the THI in our study, the elderly women presented scores superior to the men, which differs from some previous studies21 23 26 but agrees with another.2 A higher score in the evaluated women indicates that the impact provoked by the tinnitus is higher, causing a greater restriction in the social activities. Research shows that women are more careful regarding their health and that preventive care, for example, is not such an integral part of men's routine.27 In addition, elderly women present a self-perception regarding health that is more negative than men,28 which must be taken into account in the execution of evaluations and treatments to be prescribed for them. This may have influenced the results obtained in the research.

In the evaluation of quality of life, carried out through the WHOQOL-OLD, we observed that the score was similar in all evaluated domains, which is comparable to the results obtained in national studies with elderly individuals from community groups and who practice physical activities.29 30 The data was also similar to that obtained in studies carried out in other countries.31 32 In one of these studies, however, the score in the operation of the sensory domain was inferior to the one obtained in our study.32

The correlation analysis between the score of both instruments and the classification of the THI and the WHOQOL-OLD domains showed an association between THI and the operation of the sensory domain and the total score of the WHOQOL-OLD. These results confirm the compromise of the quality of life of the elderly with tinnitus. The higher the THI score (higher discomfort provoked by the tinnitus), the lesser the score in the WHOQOL-OLD (the lesser the quality of life).

A study that used the THI and WHOQOL-bref (abbreviated instrument of evaluation of quality of life developed by WHO) showed that the quality of life of the elderly with tinnitus may be affected, especially if the elder presents insomnia.8 In another research that also used the THI and WHOQOL-bref, the results also showed a correlation with the functional and emotional domains.5 The analysis of the quality of life in the elderly with or without tinnitus

is noteworthy among the individuals with the symptom; the score in the WHOQOL-bref is significantly smaller in all domains.33

Although the studies mentioned use another version of the quality of life evaluation instrument, they helped corroborate the findings in our research, whereby tinnitus harms the quality of life of the elderly. This fact must be taken into account by the professionals at the moment of the evaluation and treatment of the individuals. Therefore, elderly, which often suffer from several health disorders that compromise their autonomy, independence, and quality of life, may present tinnitus, further decreasing their wellbeing sensation. An interdisciplinary approach, however, can promote a better study of the symptom presented, helping not only in the process of evaluation and diagnosis, but also in the establishment of the appropriate treatment for each case, contributing to an improvement in the quality of life.

Conclusion

The results obtained in our study prove that the quality of life of the elderly individuals evaluated is related to a discomfort caused by the tinnitus.