| Literature DB >> 28049641 |
Leslie Skeith1, Marc Carrier1,2, Susan E Robinson3, Samah Alimam3, Marc A Rodger1,2,4.
Abstract
We performed a meta-analysis to evaluate the risk of venous thromboembolism (VTE) in pregnant women with essential thrombocythemia. Twenty-one trials and 756 pregnancies met inclusion criteria. The absolute VTE risk in the antepartum period is not above a threshold where low-molecular-weight heparin (LMWH) prophylaxis is clearly indicated or below a threshold where LMWH should be withheld (2.5%; 95% CI, 1.3-4.3). Postpartum, the absolute VTE risk is above a threshold where postpartum LMWH prophylaxis should be considered (4.4%; 95% CI, 1.2-9.5).Entities:
Mesh:
Substances:
Year: 2017 PMID: 28049641 DOI: 10.1182/blood-2016-09-728006
Source DB: PubMed Journal: Blood ISSN: 0006-4971 Impact factor: 22.113