Literature DB >> 2804696

Jaundiced Gunn rats have increased synaptic delays in the ventral cochlear nucleus.

S Zhang1, R E Wickesberg, D Oertel.   

Abstract

Recordings were made in vitro from cochlear nuclei of Gunn rats, a strain with a recessive mutation that predisposes rats to hyperbilirubinemia at birth. Delays between shocks to the auditory nerve and earliest synaptic responses of the cochlear nuclear neurons were on average longer in Gunn rats than in heterozygotes. Injections of sulfonamide further increased average synaptic delays in jaundiced rats. Responses to injected current in rats were like those in mice.

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Year:  1989        PMID: 2804696     DOI: 10.1016/0006-8993(89)91043-3

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  2 in total

1.  Acute hyperbilirubinaemia induces presynaptic neurodegeneration at a central glutamatergic synapse.

Authors:  Martin D Haustein; David J Read; Joern R Steinert; Nadia Pilati; David Dinsdale; Ian D Forsythe
Journal:  J Physiol       Date:  2010-10-11       Impact factor: 5.182

2.  Effects of Hyperbilirubinemia on Auditory Brainstem Response of Neonates Treated with Phototherapy.

Authors:  Negin Salehi; Fereshte Bagheri; Hamid Ramezani Farkhani
Journal:  Iran J Otorhinolaryngol       Date:  2016-01
  2 in total

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