Literature DB >> 2804673

Adaptation of the quantitative 2-[14C]deoxyglucose method for use in freely moving rats.

A M Crane1, L J Porrino.   

Abstract

A procedure for venous and arterial catheterization is described which allows the quantitative 2-[14C]deoxyglucose method to be applied to freely moving animals for behavioral and pharmacological studies. The catheterization method is rapid, minimally invasive, and requires no complicated equipment. Physiological conditions and rates of cerebral glucose utilization in freely moving rats and in restrained rats have been compared. The results demonstrate that local cerebral glucose utilization can readily be measured in freely moving animals engaged in behavioral experiments.

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Year:  1989        PMID： 2804673     DOI： 10.1016/0006-8993(89)91137-2

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  16 in total

1.  Differential metabolic activity in the striosome and matrix compartments of the rat striatum during natural behaviors.

Authors:  Lucy L Brown; Samuel M Feldman; Diane M Smith; James R Cavanaugh; Robert F Ackermann; Ann M Graybiel
Journal:  J Neurosci       Date:  2002-01-01       Impact factor: 6.167

2.  Regional elevations in microglial activation and cerebral glucose utilization in frontal white matter tracts of rhesus monkeys following prolonged cocaine self-administration.

Authors:  Hilary R Smith; Thomas J R Beveridge; Susan H Nader; Michael A Nader; Linda J Porrino
Journal:  Brain Struct Funct       Date:  2019-02-12       Impact factor: 3.270

3.  Local cerebral glucose utilization in rats exposed to an enriched environment: a comparison to impoverishment.

Authors:  A K Läck; K E Gill; L J Porrino
Journal:  Pharmacol Biochem Behav       Date:  2010-07-27       Impact factor: 3.533

4.  Withdrawal from extended-access cocaine self-administration results in dysregulated functional activity and altered locomotor activity in rats.

Authors:  Erin S Calipari; Thomas J R Beveridge; Sara R Jones; Linda J Porrino
Journal:  Eur J Neurosci       Date:  2013-10-13       Impact factor: 3.386

5.  Functional consequences of acute cocaine treatment depend on route of administration.

Authors:  L J Porrino
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

6.  Functional brain activity is globally elevated by dopamine D2 receptor knockdown in the ventral tegmental area.

Authors:  Tamriage A Martin; Hilary R Smith; Deborah J Luessen; Rong Chen; Linda J Porrino
Journal:  Brain Res       Date:  2019-11-11       Impact factor: 3.252

7.  Patterns of functional activity associated with cocaine self-administration in the rat change over time.

Authors:  Darrel J Macey; Wendy N Rice; Cory S Freedland; Christopher T Whitlow; Linda J Porrino
Journal:  Psychopharmacology (Berl)       Date:  2003-12-11       Impact factor: 4.530

8.  Metabolic mapping of the effects of intravenous methamphetamine administration in freely moving rats.

Authors:  F E Pontieri; A M Crane; L S Seiden; M S Kleven; L J Porrino
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

9.  Detection of visual activation in the rat brain using 2-deoxy-2-[(18)F]fluoro-D: -glucose and statistical parametric mapping (SPM).

Authors:  M L Soto-Montenegro; J J Vaquero; J Pascau; J D Gispert; P García-Barreno; M Desco
Journal:  Mol Imaging Biol       Date:  2008-11-27       Impact factor: 3.488

10.  Differential development of tolerance to the functional and behavioral effects of repeated baclofen treatment in rats.

Authors:  T J R Beveridge; H R Smith; L J Porrino
Journal:  Pharmacol Biochem Behav       Date:  2013-03-13       Impact factor: 3.533
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