| Literature DB >> 28046116 |
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Abstract
[This corrects the article DOI: 10.1371/journal.pone.0050199.].Entities:
Year: 2017 PMID: 28046116 PMCID: PMC5207491 DOI: 10.1371/journal.pone.0169498
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 4Cell-intrinsic requirement for IL-7Rα, but not TSLPR, signaling in CD8 T cell response to Influenza A.
Lethally irradiated CD45.1 BoyJ mice were reconstituted with (A) 9:1 IL-7Rα449F:BoyJ or (B) 1:1 TSLPR-/-:BoyJ bone-marrow and allowed to recover for 6–8 weeks. Mice were infected with 5HAU of PR8 and the T cell response was analyzed at day 9 post-infection. CD8 T cells were stained for CD45.1 and CD45.2 to identify WT or mutant derived cells. Each population was analyzed for the percent of total CD8 T cells that recognize the NP366–374 tetramer. Data shown is from one representative experiment of two experiments, n = 3–7. *p<0.05 by Student’s t-test.