Literature DB >> 28045630

Outcomes of Vestibular Schwannoma Surgery among the Elderly.

Michael J Sylvester1, Darshan N Shastri2, Viral M Patel1, Milap D Raikundalia1, Jean Anderson Eloy1,2,3,4, Soly Baredes1,3, Yu-Lan Mary Ying1.   

Abstract

Objective To compare comorbidities and in-hospital complications between elderly and nonelderly patients undergoing vestibular schwannoma (VS) surgery. To examine average length of stay (LOS) and hospital charges among elderly patients. Study Design Population-based inpatient registry analysis. Setting Academic medical center. Subjects and Methods Retrospective analysis of the National Inpatient Sample for patients undergoing VS surgery from 2002 to 2010: 4137 patients met inclusion criteria, with 519 (12.5%) in the elderly cohort (≥65 years). Outcomes of elderly and nonelderly (<65 years) patient cohorts were compared. Results Compared with the nonelderly cohort, the elderly cohort had more comorbidities, including diabetes mellitus, hypertension, and pulmonary disease (all P < .001). Elderly patients had longer LOS (6.5 vs 5.4 days; P = .001) but did not incur significantly greater hospital charges. Rates of cerebrospinal fluid leak, meningitis, and facial nerve injury did not vary significantly between groups. The elderly cohort experienced higher rates of in-hospital complications, including acute cardiac events, iatrogenic cerebrovascular infarction/hemorrhage, postoperative bleeding (hemorrhage/hematoma), and in-hospital mortality (all P < .05). In binary logistic regression, correcting for patient demographics and presence of comorbidities, elderly status was associated with 1.848 (95% confidence interval, 1.167-2.927; P = .009) greater odds of medical complications and 13.188 (95% confidence interval, 1.829-95.113; P = .011) greater odds of in-hospital mortality. Conclusion Elderly patients undergoing VS surgery have more comorbidities, in-hospital complications, and longer LOS than nonelderly patients. The elderly cohort had a greater rate of in-hospital mortality, though rare. Interestingly, elderly patients did not have a higher rate of many known complications associated with VS surgery and did not incur more hospital charges.

Entities:  

Keywords:  HCUP; Nationwide Inpatient Sample (NIS); acoustic neuroma; cerebrospinal fluid leak; elderly surgical outcomes; geriatric surgical oncology; in-hospital mortality; postoperative outcomes; surgery complications; vestibular schwannoma surgery

Mesh:

Year:  2016        PMID: 28045630     DOI: 10.1177/0194599816677522

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  3 in total

1.  Stereotactic radiosurgery and fractionated stereotactic radiosurgery for vestibular schwannomas: A comparison of clinical outcomes from the RSSearch patient registry.

Authors:  Raj Singh; Hayden Ansinelli; Jan Jenkins; Joanne Davis; Sanjeev Sharma; John Austin Vargo
Journal:  J Radiosurg SBRT       Date:  2019

2.  Surgical Management of Intracranial Meningiomas in the Elderly: Early and Long-term Outcomes.

Authors:  Tomasz Czernicki
Journal:  Clin Interv Aging       Date:  2020-12-30       Impact factor: 4.458

3.  Long non-coding RNA BRCAT54 sponges microRNA-21 in vestibular schwannoma to suppress cell proliferation.

Authors:  Gang Xiao; Bin Huang; Ming Guo; Chaoxin Long; Pingan Li; Bin Zhong; Chuncheng Guan
Journal:  Bioengineered       Date:  2022-02       Impact factor: 3.269

  3 in total

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