PRIMARY OBJECTIVE: To assess and compare the parasympathetic state of individuals in healthy vs concussion groups, by measuring cardiovascular metrics under resting and baroreflex conditions using a squat-stand manoeuvre. RESEARCH DESIGN: This was a retrospective mixed-method study, with participants who sustained a medically diagnosed sport concussion (n = 12), being tested within 72-hours post-injury. METHODS AND PROCEDURES: Participant's heart rate (Electrocardiogram, ECG) and blood pressure (finger plethysmography) data was collected during rest and during 10-second squat-stands (10SS, 0.05 Hz). Blood pressure and heart rate standard deviation data was analysed in the 0-5 seconds and 6-10 seconds periods of squatting and standing. Resting and baroreflex ECG data were analysed via Fourier Transformations for %Low Frequency and %High Frequency (%LF and %HF). RESULTS: The control group alleviated more pressure and had a significantly higher standard deviation of heart rate during the 6-10 seconds of squatting (p < 0.05). Overall heart rate standard deviation in the concussion group was significantly lower than healthy controls when standing (p < 0.05). There were no differences in %LF and % HF between groups or between rest and 10SS. CONCLUSION: This study provides preliminary evidence that autonomic function is dysregulated following mTBI within the initial 72 hours of injury.
PRIMARY OBJECTIVE: To assess and compare the parasympathetic state of individuals in healthy vs concussion groups, by measuring cardiovascular metrics under resting and baroreflex conditions using a squat-stand manoeuvre. RESEARCH DESIGN: This was a retrospective mixed-method study, with participants who sustained a medically diagnosed sport concussion (n = 12), being tested within 72-hours post-injury. METHODS AND PROCEDURES: Participant's heart rate (Electrocardiogram, ECG) and blood pressure (finger plethysmography) data was collected during rest and during 10-second squat-stands (10SS, 0.05 Hz). Blood pressure and heart rate standard deviation data was analysed in the 0-5 seconds and 6-10 seconds periods of squatting and standing. Resting and baroreflex ECG data were analysed via Fourier Transformations for %Low Frequency and %High Frequency (%LF and %HF). RESULTS: The control group alleviated more pressure and had a significantly higher standard deviation of heart rate during the 6-10 seconds of squatting (p < 0.05). Overall heart rate standard deviation in the concussion group was significantly lower than healthy controls when standing (p < 0.05). There were no differences in %LF and % HF between groups or between rest and 10SS. CONCLUSION: This study provides preliminary evidence that autonomic function is dysregulated following mTBI within the initial 72 hours of injury.
Authors: Daniel L Huber; Danny G Thomas; Michael Danduran; Timothy B Meier; Michael A McCrea; Lindsay D Nelson Journal: J Athl Train Date: 2019-08-14 Impact factor: 2.860
Authors: Marcin Gruszecki; Gemma Lancaster; Aneta Stefanovska; J Patrick Neary; Ryan T Dech; Wojciech Guminski; Andrzej F Frydrychowski; Jacek Kot; Pawel J Winklewski Journal: Sci Rep Date: 2018-02-15 Impact factor: 4.379
Authors: Limin Wu; Suk-Tak Chan; William J Edmiston; Gina Jin; Emily S Levy; Kenneth K Kwong; Rebekah Mannix; William P Meehan; Fortunate F Chifamba; Jonathan O Lipton; Michael J Whalen; Yin-Ching I Chen Journal: J Cereb Blood Flow Metab Date: 2021-07-06 Impact factor: 6.960