Literature DB >> 28044151

[3+2] Cycloaddition of azide with aldehyde hydrazone through an aminyl radical-polar crossover strategy.

Zhongkai Wu1, Pan Xu1, Nengneng Zhou1, Yingqian Duan1, Muliang Zhang1, Chengjian Zhu2.   

Abstract

A novel approach to obtain functionalized tetrazoles by a [3+2] cycloaddition of azide with aldehyde hydrazone is reported. This reaction features a broad substrate scope and mild reaction conditions through an aminyl radical-polar crossover strategy.

Entities:  

Year:  2017        PMID: 28044151     DOI: 10.1039/c6cc08779e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Synthesis of α-Branched Amines by Three- and Four-Component C-H Functionalization Employing a Readily Diversifiable Hydrazone Directing Group.

Authors:  Daniel S Brandes; Alex D Muma; Jonathan A Ellman
Journal:  Org Lett       Date:  2021-12-09       Impact factor: 6.005

2.  Iodine(III) Reagents in Radical Chemistry.

Authors:  Xi Wang; Armido Studer
Journal:  Acc Chem Res       Date:  2017-06-21       Impact factor: 22.384

  2 in total

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