Literature DB >> 28042161

Suspected immune-mediated neutropenia and corticosteroid responsive pancytopenia in a Portuguese water dog.

Ellen B Denstedt1.   

Abstract

An 8-year-old spayed Portuguese water dog was presented with dysuria, lethargy, and anorexia. A profound neutropenia and pancytopenia were identified. Bone marrow aspirates revealed neutrophilic hyperplasia, a significant left shift, and toxic changes, suggesting immune-mediated destruction as a likely underlying mechanism. Immunosuppressive therapy was instituted and clinical signs improved.

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Year:  2017        PMID： 28042161      PMCID： PMC5157745     

Source DB:  PubMed          Journal:  Can Vet J        ISSN： 0008-5286            Impact factor:   1.008


  10 in total

Review 1.  Neutropenia in dogs and cats: causes and consequences.

Authors:  Amy N Schnelle; Anne M Barger
Journal:  Vet Clin North Am Small Anim Pract       Date:  2011-11-16       Impact factor: 2.093

Review 2.  Diagnosis and management of primary autoimmune neutropenia in children: insights for clinicians.

Authors:  Piero Farruggia; Carlo Dufour
Journal:  Ther Adv Hematol       Date:  2015-02

3.  Evaluation of clinicopathologic features, response to treatment, and risk factors associated with idiopathic neutropenia in dogs: 11 cases (1990-2002).

Authors:  Cory D Brown; Nolie K Parnell; Rhonda L Schulman; Cassandra G Brown; Nita W Glickman; Larry Glickman
Journal:  J Am Vet Med Assoc       Date:  2006-07-01       Impact factor: 1.936

4.  Primary immune-mediated neutropenia in a cat.

Authors:  Carly E Waugh; Katherine D Scott; Laura K Bryan
Journal:  Can Vet J       Date:  2014-11       Impact factor: 1.008

5.  Neutropenia in dogs and cats: a retrospective study of 261 cases.

Authors:  M R Brown; K S Rogers
Journal:  J Am Anim Hosp Assoc       Date:  2001 Mar-Apr       Impact factor: 1.023

6.  Immune mediated neutropenia in man and animals: a review.

Authors:  W R Chickering; K W Prasse
Journal:  Vet Clin Pathol       Date:  1981       Impact factor: 1.180

7.  Evaluation of antineutrophil IgG antibodies in persistently neutropenic dogs.

Authors:  Douglas J Weiss
Journal:  J Vet Intern Med       Date:  2007 May-Jun       Impact factor: 3.333

8.  Pure white cell aplasia in a dog.

Authors:  Douglas J Weiss; Michael Henson
Journal:  Vet Clin Pathol       Date:  2007-12       Impact factor: 1.180

9.  Immune mediated neutropenia and thrombocytopenia in 3 giant schnauzers.

Authors:  Cheryl L Vargo; Susan M Taylor; Deborah M Haines
Journal:  Can Vet J       Date:  2007-11       Impact factor: 1.008

10.  Immune-mediated neutropenia in 2 dogs.

Authors:  P M McManus; C Litwin; L Barber
Journal:  J Vet Intern Med       Date:  1999 Jul-Aug       Impact factor: 3.333
  10 in total

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