Literature DB >> 28039598

Patient acceptability and experiences of therapeutic switching of proton pump inhibitors within the National Preferred Drugs initiative in Ireland.

G O'Connor1,2, D O'Keeffe3,4, C Darker4, B O'Shea4.   

Abstract

INTRODUCTION: A 'Preferred Drugs' initiative was introduced into Ireland in 2013. This identified a single recommended drug to be prescribed to patients requiring treatment from a particular class of drugs. AIMS: This study investigates how patients on established proton pump inhibitor (PPI) therapy experienced the therapeutic switching of their medication to the 'preferred drug', and the extent to which they regarded it as an acceptable practice.
METHODS: The experiences of 61 patients on established proton pump inhibitor (PPI) therapy were sought before and after their drug was switched to the 'preferred drug'.
RESULTS: Eighty per cent of patients were happy to switch medications. When asked for their opinions on medications in general, 71% felt doctors should prescribe the least expensive medication, 84% agreed that all licensed medications were safe while 67% felt their GP changing medication for cost reasons was safe. After 8 weeks, 20% of patients had switched back to their old PPI. When asked how they felt about their medication change, 74% felt happy or pleased.
CONCLUSIONS: The majority of patients in our study were satisfied to have their medication switched. However, prescribers should be mindful that 1 in 5 patients encountered problems as a result of the switching process.

Entities:  

Keywords:  Drug costs; Drug substitution; Preferred drugs; Proton pump inhibitors

Mesh:

Substances:

Year:  2016        PMID: 28039598     DOI: 10.1007/s11845-016-1535-2

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  21 in total

1.  Physicians' views of formularies: implications for Medicare drug benefit design.

Authors:  Bruce E Landon; James D Reschovsky; David Blumenthal
Journal:  Health Aff (Millwood)       Date:  2004 Jan-Feb       Impact factor: 6.301

Review 2.  A systematic literature review assessing the directional impact of managed care formulary restrictions on medication adherence, clinical outcomes, economic outcomes, and health care resource utilization.

Authors:  Laura E Happe; Deanna Clark; Edana Holliday; Tramaine Young
Journal:  J Manag Care Spec Pharm       Date:  2014-07

Review 3.  Switching antidepressants after a first selective serotonin reuptake inhibitor in major depressive disorder: a systematic review.

Authors:  Henricus G Ruhé; Jochanan Huyser; Jan A Swinkels; Aart H Schene
Journal:  J Clin Psychiatry       Date:  2006-12       Impact factor: 4.384

4.  Patient perceptions of generic medicines: a mixed-methods study.

Authors:  Suzanne Dunne; Bill Shannon; Colum Dunne; Walter Cullen
Journal:  Patient       Date:  2014       Impact factor: 3.883

5.  Esomeprazole (40 mg) compared with lansoprazole (30 mg) in the treatment of erosive esophagitis.

Authors:  Donald O Castell; Peter J Kahrilas; Joel E Richter; Nimish B Vakil; David A Johnson; Seth Zuckerman; Wendy Skammer; Jeffrey G Levine
Journal:  Am J Gastroenterol       Date:  2002-03       Impact factor: 10.864

6.  What are the obstacles to generic substitution? An assessment of the behaviour of prescribers, patients and pharmacies during the first year of generic substitution in Sweden.

Authors:  Karolina Andersson; Christian Sonesson; Max Petzold; Anders Carlsten; Knut Lönnroth
Journal:  Pharmacoepidemiol Drug Saf       Date:  2005-05       Impact factor: 2.890

7.  Evidence for therapeutic equivalence of lansoprazole 30mg and esomeprazole 40mg in the treatment of erosive oesophagitis.

Authors:  Colin W Howden; E David Ballard; Weining Robieson
Journal:  Clin Drug Investig       Date:  2002       Impact factor: 2.859

8.  Beliefs about generic drugs among elderly adults in hospital-based primary care practices.

Authors:  Alice Iosifescu; Ethan A Halm; Thomas McGinn; Albert L Siu; Alex D Federman
Journal:  Patient Educ Couns       Date:  2008-11

9.  Is 50 cent the price of the optimal copayment? - a qualitative study of patient opinions and attitudes in response to a 50 cent charge on prescription drugs in a publicly funded health system in Ireland.

Authors:  Sarah-Jo Sinnott; Marie Guinane; Helen Whelton; Stephen Byrne
Journal:  BMC Health Serv Res       Date:  2013-01-10       Impact factor: 2.655

10.  Interventions designed to improve the quality and efficiency of medication use in managed care: a critical review of the literature - 2001-2007.

Authors:  Christine Y Lu; Dennis Ross-Degnan; Stephen B Soumerai; Sallie-Anne Pearson
Journal:  BMC Health Serv Res       Date:  2008-04-07       Impact factor: 2.655

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.