Literature DB >> 28035622

The HUGE formula (hematocrit, urea, gender) for screening for chronic kidney disease in elderly patients: a study of diagnostic accuracy.

Carlos G Musso1,2, Eduardo de Los Rios3, Manuel Vilas4, Sergio Terrasa5,6, Griselda Bratti4, Federico Varela4, Guillermo Rosa Diez4, Jose Jauregui7, Daniel Luna3.   

Abstract

Chronically reduced glomerular filtration rate (GFR) in old people does not always mean that they suffer from chronic kidney disease (CKD) since their GFR can just be reduced by aging. The HUGE equation has been recently described and validated in Spain for screening CKD without taking into account the patient's GFR value. This equation is based on patient's hematocrit, plasma urea levels and gender. The present study documented that the HUGE equation had and acceptable performance for screening CKD in elderly Argentine patients.

Entities:  

Keywords:  Chronic kidney disease; Elderly; HUGE equation

Mesh：

Substances：

Year:  2016        PMID： 28035622     DOI： 10.1007/s11255-016-1486-6

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN： 0301-1623            Impact factor:   2.370


  5 in total

1.  [The haematocrit, urea and gender formula: association with overall mortality in a cohort of elderly patients followed up for 8 years].

Authors:  Manuel Heras; María Teresa Guerrero; Angélica Muñoz; Elena Ridruejo; María José Fernández-Reyes
Journal:  Rev Esp Geriatr Gerontol       Date:  2014-11-30

2.  The value of a formula including haematocrit, blood urea and gender (HUGE) as a screening test for chronic renal insufficiency.

Authors:  J A Alvarez-Gregori; N R Robles; C Mena; R Ardanuy; R Jauregui; J F Macas-Nu Nunez
Journal:  J Nutr Health Aging       Date:  2011-06       Impact factor: 4.075

3.  The HUGE formula (hematocrit, urea and gender): association with cardiovascular risk.

Authors:  N R Robles; F J Felix; D Fernandez-Berges; J Perez-Castán; M J Zaro; L Lozano; P Alvarez-Palacios; A Garcia-Trigo; V Tejero; Y Morcillo; A B Hidalgo
Journal:  Eur Rev Med Pharmacol Sci       Date:  2013-07       Impact factor: 3.507

4.  Physiological similarities and differences between renal aging and chronic renal disease.

Authors:  Carlos G Musso; Juan F Macías Nuñez; Dimitrios G Oreopoulos
Journal:  J Nephrol       Date:  2007 Sep-Oct       Impact factor: 3.902

5.  The H.U.G.E. Formula (Hematocrit, Urea, Sex) for Screening Chronic Kidney Disease (CKD) in an Age-Stratified General Population.

Authors:  N R Robles; F J Felix; L Lozano; I Miranda; D Fernandez-Berges; J F Macías
Journal:  J Nutr Health Aging       Date:  2015-06       Impact factor: 4.075
  5 in total

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