Literature DB >> 2803478

Elevation of the levels of SmB, B' and D proteins but not that of the La (SS-B) antigen during HSV infections.

N G Sharpe1, D Isenberg, D G Williams, D S Latchman.   

Abstract

Three Sm proteins, B, B' and D, which are highly immunoreactive in systemic lupus erythematosus (SLE), increase in abundance in Vero cells infected with laboratory strains and clinical isolates of herpes simplex virus (HSV) types 1 and 2. The autoimmune antigen La (SS-B) does not accumulate in identical infections. The significance of the Sm antigen accumulation is discussed in terms of its possible role in HSV infection and in connection with the origin of autoantibodies in SLE.

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Year:  1989        PMID: 2803478     DOI: 10.1016/s0896-8411(89)80008-3

Source DB:  PubMed          Journal:  J Autoimmun        ISSN: 0896-8411            Impact factor:   7.094


  5 in total

1.  The herpes simplex virus virion protein Vmw65 transcriptionally activates the gene encoding the U4 snRNA but not that encoding the U2 snRNA during lytic infection.

Authors:  D S Latchman
Journal:  Biochem J       Date:  1991-04-15       Impact factor: 3.857

2.  La/SSB ribonucleoprotein levels increased in transformed cells.

Authors:  R P Rother; P S Thomas
Journal:  Clin Exp Immunol       Date:  1991-03       Impact factor: 4.330

3.  The herpes simplex virus immediate-early protein ICP27 stimulates the transcription of cellular Alu repeated sequences by increasing the activity of transcription factor TFIIIC.

Authors:  K L Jang; D S Latchman
Journal:  Biochem J       Date:  1992-06-15       Impact factor: 3.857

4.  Adenovirus infection induces loss of HLA class I and CD3 antigens, but does not induce cell surface presentation of the La (SS-B) autoantigen.

Authors:  R Peek; J R Westphal; G J Pruijn; A J Van der Kemp; W J Van Venrooij
Journal:  Clin Exp Immunol       Date:  1994-06       Impact factor: 4.330

5.  Antiviral activity of (+)-sattabacin against varicella zoster.

Authors:  Serena R Mancha; Christopher M Regnery; Joshua R Dahlke; Kenneth A Miller; David J Blake
Journal:  Bioorg Med Chem Lett       Date:  2012-11-16       Impact factor: 2.823

  5 in total

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