Literature DB >> 28031574

Cancer: Microtubule-straightening compound widens the therapeutic window.

Alexandra Flemming.   

Abstract

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Year:  2016        PMID: 28031574     DOI: 10.1038/nrd.2016.275

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  1 in total

1.  The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.

Authors:  Michal Wieczorek; Joseph Tcherkezian; Cynthia Bernier; Andrea E Prota; Sami Chaaban; Yannève Rolland; Claude Godbout; Mark A Hancock; Joseph C Arezzo; Ozhan Ocal; Cecilia Rocha; Natacha Olieric; Anita Hall; Hui Ding; Alexandre Bramoullé; Matthew G Annis; George Zogopoulos; Patrick G Harran; Thomas M Wilkie; Rolf A Brekken; Peter M Siegel; Michel O Steinmetz; Gordon C Shore; Gary J Brouhard; Anne Roulston
Journal:  Sci Transl Med       Date:  2016-11-16       Impact factor: 17.956

  1 in total
  1 in total

1.  Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis.

Authors:  Yuting Yan; Yan Zhou; Juntao Li; Zhongnan Zheng; Yabin Hu; Lei Li; Wei Wu
Journal:  Cell Death Dis       Date:  2021-10-07       Impact factor: 8.469

  1 in total

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