| Literature DB >> 28026886 |
Hiroki Yoshihara1, Tadashi Kumamoto2, Rintaro Ono1, Keiko Akahane3, Taiki Nozaki4, Shogo Kobayashi5, Atsushi Kikuta5, Seiichi Matsumoto6, Daisuke Hasegawa1, Chitose Ogawa1, Atsushi Manabe1.
Abstract
We describe the case of a 13-year-old girl with multifocal disseminated Ewing sarcoma family of tumor (ESFT) who received a 5/8 human leukocyte antigen-matched haploidentical hematopoietic cell transplantation to generate a graft-versus-tumor effect. The patient had grade 2 acute graft-versus-host disease (GVHD) of the skin and chronic GVHD nausea and abdominal pain that required prednisolone for 17 months, but has been free from ESFT for 3 years 10 months after therapy. The present case suggests a beneficial effect of haploidentical hematopoietic cell transplantation in disseminated ESFT.Entities:
Keywords: Ewing sarcoma; graft-versus-host disease; graft-versus-tumor effect; hematopoietic stem cell transplantation; killer cell immunoglobulin-like receptor
Mesh：
Year: 2016 PMID： 28026886 DOI： 10.1111/ped.13195
Source DB: PubMed Journal: Pediatr Int ISSN： 1328-8067 Impact factor: 1.524