Literature DB >> 28025794

Alterations in corneal epithelial thickness in patients with congenital myogenic eyelid ptosis.

Aysun Sanal Dogan1, Mutlu Acar2, Mustafa Kosker2, Nese Arslan2, Canan Gurdal2.   

Abstract

PURPOSE: To evaluate whether the corneal epithelial thickness (CET) maps obtained by optical coherence tomography (OCT) of the congenital myogenic eyelid ptosis differ from controls.
METHODS: CET maps of 13 patients with congenital myogenic eyelid ptosis (m/f = 9/4; mean age 20.5 ± 7.5) and randomly selected one eye of 13 controls (m/f = 7/6; mean age 21.5 ± 6.5) were investigated. Three pachymetry scans of each eye were performed by OCT (RTVue-XR, Optovue Inc., USA), and the scan with the highest signal strength index was selected for the analysis.
RESULTS: In ptosis group: Minimum corneal epithelial thickness was thinner (p = 0.029), standard deviation of thickness was higher (p = 0.039), the negative of min-max values were higher (p = 0.007). This difference was originating from the significant thinness of the superior sectors (S, SN, ST) of the corneal epithelium than the inferior counterparts (I, IT, IN) (p = 0.001, p = 0.017, p = 0.002), respectively. There was no difference regarding total corneal thickness measurements.
CONCLUSIONS: The mechanic effects of ptotic eyelid to the ocular surface may reshape the corneal epithelium, which can be objectively detected by OCT.

Entities:  

Keywords:  Cornea; Cornea epithelium; Corneal epithelial thickness; Myogenic eyelid ptosis; Optical coherence tomography

Mesh:

Year:  2016        PMID: 28025794     DOI: 10.1007/s10792-016-0419-9

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN: 0165-5701            Impact factor:   2.031


  15 in total

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3.  Corneal epithelial thickness mapping using Fourier-domain optical coherence tomography for detection of form fruste keratoconus.

Authors:  Cyril Temstet; Otman Sandali; Nacim Bouheraoua; Taous Hamiche; Alice Galan; Mohamed El Sanharawi; Elena Basli; Laurent Laroche; Vincent Borderie
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Journal:  Cornea       Date:  2016-04       Impact factor: 2.651

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7.  Pachymetry map of corneal epithelium in children wearing orthokeratology contact lenses.

Authors:  Yishan Qian; Feng Xue; Jia Huang; Xiaomei Qu; Xingtao Zhou; Devan Van Lanen-Wanek
Journal:  Curr Eye Res       Date:  2013-12-10       Impact factor: 2.424

8.  In vivo three-dimensional corneal epithelium imaging in normal eyes by anterior-segment optical coherence tomography: a clinical reference study.

Authors:  Anastasios John Kanellopoulos; George Asimellis
Journal:  Cornea       Date:  2013-11       Impact factor: 2.651

9.  [Comparative study of refractive errors in simple congenital myogenic ptosis and control children].

Authors:  M A Pérez-Iñigo; I González; F Mayoral; C Ferrer; F M Honrubia
Journal:  Arch Soc Esp Oftalmol       Date:  2008-10

10.  Age-related changes in human corneal epithelial thickness measured with anterior segment optical coherence tomography.

Authors:  Yujing Yang; Jiaxu Hong; Sophie X Deng; Jianjiang Xu
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-07-22       Impact factor: 4.799

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  2 in total

1.  Evaluation of the Effect of Dermatochalasis and Upper Eyelid Blepharoplasty Surgery on Corneal Epithelial Thickness Alterations.

Authors:  Neşe Arslan; Sücattin İlker Kocamış; Huri Sabur; Mutlu Acar
Journal:  Aesthetic Plast Surg       Date:  2022-10-10       Impact factor: 2.708

2.  Clinical observations of corneal topographic and tomographic changes in congenital ptosis eyes: a study in China.

Authors:  Jianqin Shen; Huiyan Li; Yanhong Chen; Lan Liu; Hongguang Cui
Journal:  Int Ophthalmol       Date:  2022-10-21       Impact factor: 2.029

  2 in total

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