Literature DB >> 28025388

Nosema ceranae Winter Control: Study of the Effectiveness of Different Fumagillin Treatments and Consequences on the Strength of Honey Bee (Hymenoptera: Apidae) Colonies.

Y Mendoza1, S Diaz-Cetti1, G Ramallo1, E Santos2, M Porrini3, C Invernizzi2.   

Abstract

Overview: In Uruguay, colonies of honey bees moving to Eucalyptus grandis plantation in autumn habitually become infected with the microsporidian Nosema ceranae , a parasite that attacks the digestive system of bees. Beekeepers attributed to N. ceranae depopulation of the colonies that often occurs at the end of the blooming period, and many use the antibiotic fumagillin to reduce the level of infection. The aim of this study was to compare the effectiveness of four different fumagillin treatments and determine how this antibiotic affects the strength of the colonies during the winter season. The colonies treated with fumagillin in July showed less spore load at the end of applications, being the most effective the following treatments: the four applications sprayed over bees of 30 mg of fumagillin in 100 ml of sugar syrup 1:1, and four applications of 90 mg of fumagillin in 250 ml of sugar syrup 1:1 using a feeder. However, 2 month after the treatment applications, the colonies treated with fumagillin were the same size as the untreated colonies. In September, the colonies treated and not treated with fumagillin did not differ in colony strength (adult bee population and brood area) or spores abundance. Our study demonstrates that fumagillin treatment temporarily decreased the spore load of N. ceranae , but this was not reflected in either the size of the colonies or the probability of surviving the winter regardless of the dose or the administration strategy applied. Given the results obtained, we suggest to not perform the pharmacological treatment under the conditions described in the experiment. Resumen: En Uruguay las colonias de abejas melíferas que se trasladan a las forestaciones de Eucalyptus grandis en otoño indefectiblemente se infectan con el microsporido Nosema ceranae , parásito que ataca el sistema digestivo de las abejas. Los apicultores atribuyen a N. ceranae el despoblamiento de las colonias que ocurre con frecuencia al terminar el periodo de floración y muchos emplean el antibiótico fumagilina para reducir el nivel de infección. El objetivo de este estudio fue comparar la eficacia de cuatro tratamientos diferentes con fumagilina y determinar cómo incide en la fortaleza de las colonias durante la invernada. Las colonias tratadas con fumagilina en julio presentaron una menor carga de esporas al terminar las aplicaciones, siendo los tratamientos más eficaces el de 4 aplicaciones mediante asperjado sobre las abejas de 30 mg de fumagilina en 100 ml de jarabe de azúcar 1:1, y el de 4 aplicaciones de 90 mg de fumagilina en 250 ml de jarabe de azúcar 1:1 utilizando un alimentador. Sin embargo, durante el período de experimentación, las colonias tratadas con antibiótico presentaron igual tamaño que las colonias no tratadas. En setiembre, las colonias tratadas y no tratadas con fumagilina no se diferenciaron en la intensidad de infección ni en su tamaño. En las condiciones en que se realizó el estudio, la aplicación de fumagilina disminuyó temporalmente la carga de esporas de N. ceranae pero esto no se reflejó en el tamaño de las colonias ni en la probabilidad de sobrevivir el invierno.
© The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Entities:  

Keywords:  Apis mellifera; Eucalyptus; Nosema ceranae; antibiotic; nosemosis

Mesh:

Substances:

Year:  2017        PMID: 28025388     DOI: 10.1093/jee/tow228

Source DB:  PubMed          Journal:  J Econ Entomol        ISSN: 0022-0493            Impact factor:   2.381


  7 in total

1.  Robust Transcriptional Response to Heat Shock Impacting Diverse Cellular Processes despite Lack of Heat Shock Factor in Microsporidia.

Authors:  Nora K McNamara-Bordewick; Mia McKinstry; Jonathan W Snow
Journal:  mSphere       Date:  2019-05-22       Impact factor: 4.389

2.  A call to arms: Mustering secondary metabolites for success and survival of an opportunistic pathogen.

Authors:  Nicholas Raffa; Nancy P Keller
Journal:  PLoS Pathog       Date:  2019-04-04       Impact factor: 6.823

3.  Transferrin-mediated iron sequestration suggests a novel therapeutic strategy for controlling Nosema disease in the honey bee, Apis mellifera.

Authors:  Cristina Rodríguez-García; Matthew C Heerman; Steven C Cook; Jay D Evans; Gloria DeGrandi-Hoffman; Olubukola Banmeke; Yi Zhang; Shaokang Huang; Michele Hamilton; Yan Ping Chen
Journal:  PLoS Pathog       Date:  2021-02-18       Impact factor: 6.823

4.  RNA Interference-Mediated Knockdown of Genes Encoding Spore Wall Proteins Confers Protection against Nosema ceranae Infection in the European Honey Bee, Apis mellifera.

Authors:  Nan He; Yi Zhang; Xin Le Duan; Jiang Hong Li; Wei-Fone Huang; Jay D Evans; Gloria DeGrandi-Hoffman; Yan Ping Chen; Shao Kang Huang
Journal:  Microorganisms       Date:  2021-02-27

5.  Proteasome Inhibition Is an Effective Treatment Strategy for Microsporidia Infection in Honey Bees.

Authors:  Emily M Huntsman; Rachel M Cho; Helen V Kogan; Nora K McNamara-Bordewick; Robert J Tomko; Jonathan W Snow
Journal:  Biomolecules       Date:  2021-10-29

6.  Paromomycin Reduces Vairimorpha (Nosema)ceranae Infection in Honey Bees but Perturbs Microbiome Levels and Midgut Cell Function.

Authors:  Rachel M Cho; Helen V Kogan; Annabelle B Elikan; Jonathan W Snow
Journal:  Microorganisms       Date:  2022-05-27

Review 7.  The Role of Nosema ceranae (Microsporidia: Nosematidae) in Honey Bee Colony Losses and Current Insights on Treatment.

Authors:  Pablo Jesús Marín-García; Yoorana Peyre; Ana Elena Ahuir-Baraja; María Magdalena Garijo; Lola Llobat
Journal:  Vet Sci       Date:  2022-03-11
  7 in total

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