Literature DB >> 2802479

Solitary thyroid nodule: audit shows improved care requires cytological diagnosis.

N R Wetzig1, A E Giddings.   

Abstract

An audit was conducted of all patients undergoing thyroid surgery in a district general hospital over the 8-year period during which fine needle aspiration cytology (FNAC) was introduced. Of the 252 patients, 32 (14%) were toxic and 92 (36%) had large multinodular goitres, but 118 (46%) had a solitary thyroid nodule removed to exclude neoplasm. However, only 12.7% of such resected nodules were found to be carcinomas. Where FNAC was used, the accuracy for preoperative diagnosis was 82.6% and the sensitivity for prediction of carcinoma was 87.5%. Cytology correctly predicted 81% of the colloid nodules and these may have been managed without surgery if the patient was agreeable. It is suggested that one-half of the patients with solitary thyroid nodules could have been spared operation. Analysis of the operative procedure shows that one-fifth of the neoplasms may have been more accurately dealt with had FNAC been used, and four patients could have avoided the trauma and risks of a second operation. The study suggests that FNAC and increased specialisation will improve the quality of thyroid surgery in a district general hospital.

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Year:  1989        PMID: 2802479      PMCID: PMC2499016     

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  9 in total

1.  Nodular goiter. Incidence, morphology before and after iodine prophylaxis, and clinical diagnosis.

Authors:  R P STOFFER; J W WELCH; C A HELLWIG; V E CHESKY; E N McCUSKER
Journal:  AMA Arch Intern Med       Date:  1960-07

2.  Why on earth do surgeons need quality assurance?

Authors:  J R Gumpert
Journal:  Ann R Coll Surg Engl       Date:  1988-03       Impact factor: 1.891

3.  Aspiration biopsy cytology (ABC) in nodules of the thyroid gland suspected to be malignant.

Authors:  T Löwhagen; P O Granberg; G Lundell; P Skinnari; R Sundblad; J S Willems
Journal:  Surg Clin North Am       Date:  1979-02       Impact factor: 2.741

4.  Aspiration biopsy of thyroid nodules.

Authors:  G Crile; W A Hawk
Journal:  Surg Gynecol Obstet       Date:  1973-02

5.  The significance of nontoxic thyroid nodules. Final report of a 15-year study of the incidence of thyroid malignancy.

Authors:  J B Vander; E A Gaston; T R Dawber
Journal:  Ann Intern Med       Date:  1968-09       Impact factor: 25.391

6.  Evaluation of various types of needle biopsies of the thyroid.

Authors:  C B Esselstyn; G Crile
Journal:  World J Surg       Date:  1984-08       Impact factor: 3.352

7.  Aspiration biopsy cytology of carcinoma of the thyroid.

Authors:  T Löwhagen; J S Willems
Journal:  Neth J Med       Date:  1981       Impact factor: 1.422

8.  Diagnosis of thyroid nodules. Use of fine-needle aspiration and needle biopsy.

Authors:  J M Miller; J I Hamburger; S Kini
Journal:  JAMA       Date:  1979-02-02       Impact factor: 56.272

9.  Fine-needle aspiration biopsy and the diagnosis of thyroid cancer.

Authors:  J B Anderson; A J Webb
Journal:  Br J Surg       Date:  1987-04       Impact factor: 6.939

  9 in total
  1 in total

1.  A regional study of thyroidectomy: surgical pathology suggests scope to improve quality and reduce cost.

Authors:  G Asimakopoulos; T Loosemore; R C Bowyer; G McKee; A E Giddings
Journal:  Ann R Coll Surg Engl       Date:  1995-11       Impact factor: 1.891

  1 in total

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