Literature DB >> 28018154

Antenatal Escitalopram Use and Necrotizing Enterocolitis in a Newborn: A Case Report.

Nilima Jawale1, Alok Bhutada1, Shantanu Rastogi1.   

Abstract

The increased use of antidepressants during pregnancy has been associated with adverse effects in the newborn. We report a case of antenatal escitalopram use associated with necrotizing enterocolitis in a healthy term baby. We further discuss possible mechanisms that may explain this association. With increasing evidence of association of necrotizing enterocolitis with maternal exposure to antidepressants, more studies to find out causality and methods to predict babies at risk and their prudent management are needed.

Entities:  

Keywords:  SSRIs; escitalopram; necrotizing enterocolitis; pregnancy; prenatal antidepressant-exposure syndrome; selective serotonin reuptake inhibitors; term neonate

Year:  2016        PMID： 28018154      PMCID： PMC5178814          DOI： 10.5863/1551-6776-21.6.518

Source DB:  PubMed          Journal:  J Pediatr Pharmacol Ther        ISSN： 1551-6776


  16 in total

1.  Neonatal paroxetine withdrawal syndrome.

Authors:  J A Stiskal; N Kulin; G Koren; T Ho; S Ito
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2001-03       Impact factor: 5.747

Review 2.  On categorizing gestational, birth, and neonatal complications following late pregnancy exposure to antidepressants: the prenatal antidepressant exposure syndrome.

Authors:  Salvatore Gentile
Journal:  CNS Spectr       Date:  2010-03       Impact factor: 3.790

Review 3.  Impact of maternal stress, depression and anxiety on fetal neurobehavioral development.

Authors:  Michael T Kinsella; Catherine Monk
Journal:  Clin Obstet Gynecol       Date:  2009-09       Impact factor: 2.190

Review 4.  Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications.

Authors:  Eydie L Moses-Kolko; Debra Bogen; James Perel; Amy Bregar; Kathleen Uhl; Bob Levin; Katherine L Wisner
Journal:  JAMA       Date:  2005-05-18       Impact factor: 56.272

5.  Necrotizing enterocolitis associated with in utero and breast milk exposure to the selective serotonin reuptake inhibitor, escitalopram.

Authors:  A L Potts; K L Young; B S Carter; J P Shenai
Journal:  J Perinatol       Date:  2007-02       Impact factor: 2.521

Review 6.  Is there a correlation between venlafaxine therapy during pregnancy and a higher incidence of necrotizing enterocolitis?

Authors:  Markus Treichel; Katharina Schwendener Scholl; Ulf Kessler; Alexander Joeris; Mathias Nelle
Journal:  World J Pediatr       Date:  2009-01-27       Impact factor: 2.764

7.  Severe adverse effects in a newborn with two defective CYP2D6 alleles after exposure to paroxetine during late pregnancy.

Authors:  Kari Laine; Jaakko Kytölä; Leif Bertilsson
Journal:  Ther Drug Monit       Date:  2004-12       Impact factor: 3.681

8.  Association between maternal anxiety in pregnancy and increased uterine artery resistance index: cohort based study.

Authors:  J M Teixeira; N M Fisk; V Glover
Journal:  BMJ       Date:  1999-01-16

9.  Sustained neurobehavioral effects of exposure to SSRI antidepressants during development: molecular to clinical evidence.

Authors:  T F Oberlander; J A Gingrich; M S Ansorge
Journal:  Clin Pharmacol Ther       Date:  2009-11-04       Impact factor: 6.875

10.  Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn.

Authors:  Christina D Chambers; Sonia Hernandez-Diaz; Linda J Van Marter; Martha M Werler; Carol Louik; Kenneth Lyons Jones; Allen A Mitchell
Journal:  N Engl J Med       Date:  2006-02-09       Impact factor: 91.245
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