| Literature DB >> 28017814 |
Hai Jiang1, Liu Yang2, Guo-Xu Ma3, Xu-Dong Xing2, Mei-Ling Yan2, Yan-Yan Zhang2, Qiu-Hong Wang4, Bing-You Yang2, Hai-Xue Kuang5, Xu-Dong Xu6.
Abstract
The fruits of Xanthium sibiricum Patr yielded five phenylpropanoid derivatives, named as xanthiumnolics A-E (1-5). Their structures were elucidated by spectroscopic analysis and comparison with literature data. The isolated ones were tested for their anti-inflammatory activities on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7, and compound 5 showed strong inhibitory activities with IC50 value of 8.73μM.Entities:
Keywords: Anti-inflammatory activities; Phenylpropanoids; RAW 264.7; X. sibiricum
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Year: 2016 PMID: 28017814 DOI: 10.1016/j.fitote.2016.12.007
Source DB: PubMed Journal: Fitoterapia ISSN: 0367-326X Impact factor: 2.882