Literature DB >> 28011303

The promiscuous ectonucleotidase NPP1: molecular insights into substrate binding and hydrolysis.

Vigneshwaran Namasivayam1, Sang-Yong Lee1, Christa E Müller2.   

Abstract

Entities:  

Keywords:  2′,3″-cGAMP; Cancer immunotherapy; Nucleotide pyrophosphatase 1; Substrate promiscuity; cAMP

Mesh：

Substances：

Year:  2016        PMID： 28011303     DOI： 10.1016/j.bbagen.2016.12.019

Source DB:  PubMed          Journal:  Biochim Biophys Acta Gen Subj        ISSN： 0304-4165            Impact factor:   3.770


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  12 in total

1.  Development of Novel Ecto-Nucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Tumor Immunotherapy.

Authors:  Xiang Wang; Xing Lu; Daojing Yan; Yajun Zhou; Xiangshi Tan
Journal:  Int J Mol Sci       Date:  2022-06-26       Impact factor: 6.208

Review 2.  Nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) and its inhibitors.

Authors:  Sang-Yong Lee; Christa E Müller
Journal:  Medchemcomm       Date:  2017-02-09       Impact factor: 3.597

Review 3.  Chemical and Biomolecular Strategies for STING Pathway Activation in Cancer Immunotherapy.

Authors:  Kyle M Garland; Taylor L Sheehy; John T Wilson
Journal:  Chem Rev       Date:  2022-02-02       Impact factor: 60.622

4.  ATP-degrading ENPP1 is required for survival (or persistence) of long-lived plasma cells.

Authors:  Hongsheng Wang; Ines Gonzalez-Garcia; Javier Traba; Shweta Jain; Solomon Conteh; Dong-Mi Shin; Chenfeng Qi; Yuanyuan Gao; Jiafang Sun; Sungyun Kang; Sadia Abbasi; Zohreh Naghashfar; Jeongheon Yoon; Wendy DuBois; Alexander L Kovalchuk; Michael N Sack; Patrick Duffy; Herbert C Morse
Journal:  Sci Rep       Date:  2017-12-19       Impact factor: 4.379

5.  Substrate-Dependence of Competitive Nucleotide Pyrophosphatase/Phosphodiesterase1 (NPP1) Inhibitors.

Authors:  Sang-Yong Lee; Soumya Sarkar; Sanjay Bhattarai; Vigneshwaran Namasivayam; Steven De Jonghe; Holger Stephan; Piet Herdewijn; Ali El-Tayeb; Christa E Müller
Journal:  Front Pharmacol       Date:  2017-02-15       Impact factor: 5.810

6.  Fluorescence Differentiation of ATP-related Multiple Enzymatic Activities in Synovial Fluid as a Marker of Calcium Pyrophosphate Deposition Disease using Kyoto Green.

Authors:  Nattha Yongwattana; Nutsara Mekjinda; Tulyapruek Tawonsawatruk; Itaru Hamachi; Akio Ojida; Jirarut Wongkongkatep
Journal:  Molecules       Date:  2020-03-02       Impact factor: 4.411

7.  Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39.

Authors:  Vittoria Lopez; Laura Schäkel; H J Maximilian Schuh; Michael S Schmidt; Salahuddin Mirza; Christian Renn; Julie Pelletier; Sang-Yong Lee; Jean Sévigny; Susanne Alban; Gerd Bendas; Christa E Müller
Journal:  Mar Drugs       Date:  2021-01-22       Impact factor: 5.118

8.  Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.

Authors:  Kazuki Kato; Hiroshi Nishimasu; Daisuke Oikawa; Seiichi Hirano; Hisato Hirano; Go Kasuya; Ryuichiro Ishitani; Fuminori Tokunaga; Osamu Nureki
Journal:  Nat Commun       Date:  2018-10-24       Impact factor: 14.919

Review 9.  ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors-A STING in the Tale of ENPP1.

Authors:  Kenneth I Onyedibe; Modi Wang; Herman O Sintim
Journal:  Molecules       Date:  2019-11-19       Impact factor: 4.411

10.  Crystal structures of human ENPP1 in apo and bound forms.

Authors:  Matthew L Dennis; Janet Newman; Olan Dolezal; Meghan Hattarki; Regina N Surjadi; Stewart D Nuttall; Tam Pham; Tom Nebl; Michelle Camerino; Poh Sim Khoo; Brendon J Monahan; Thomas S Peat
Journal:  Acta Crystallogr D Struct Biol       Date:  2020-08-17       Impact factor: 7.652
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