Literature DB >> 28011209

Validation of Clinical Tools for Vaginal and Vulvar Symptom Assessment in Cancer Patients and Survivors.

Anne A Eaton1, Raymond E Baser1, Barbara Seidel2, Cara Stabile2, Jocelyn P Canty2, Deborah J Goldfrank3, Jeanne Carter4.   

Abstract

INTRODUCTION: Health care professionals can play a pivotal role in promoting vulvovaginal health through assessment and appropriate intervention. AIM: To develop and validate brief clinical measurements to facilitate the identification of vulvovaginal symptoms in patients with and survivors of cancer.
METHODS: One hundred seventy-five women survivors of cancer attending a Female Sexual Medicine and Women's Health Program from September 26, 2012 through October 31, 2014 completed the Vaginal Assessment Scale (VAS) and the Vulvar Assessment Scale (VuAS)-a modified version of the VAS that targets vulvar symptoms. Pelvic examination results were recorded using a clinical examination checklist. MAIN OUTCOME MEASURES: Internal consistency of the two scales was assessed using Cronbach α, and the correlation between scales and other outcomes was reported.
RESULTS: The internal consistency measurements of the VAS and VuAS at the first visit were 0.70 and 0.68, which decreased to 0.53 and 0.66 at the last visit. The VAS composite and VuAS composite scores were moderately correlated with each other (0.42 and 0.45 at first and last visits, respectively). A strong correlation was observed between VAS pain with intercourse and Female Sexual Function Index (FSFI) pain with intercourse (-0.63 and -0.71 at the first and last visits, respectively). Worse pain with examination, worse functioning on the FSFI pain, lubrication, and total scores, and worse vulvar irritation were correlated with more severe symptoms on the VAS and VuAS.
CONCLUSION: The VAS and VuAS are simple tools that can be used by clinicians to assess health concerns in women diagnosed with and treated for cancer. Validation is needed across diverse settings and groups of women.
Copyright © 2016 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cancer; Cancer Survivorship; Sexual Health; Symptom Assessment; Vaginal Health; Vulvar Health

Mesh:

Year:  2016        PMID: 28011209      PMCID: PMC5222753          DOI: 10.1016/j.jsxm.2016.11.317

Source DB:  PubMed          Journal:  J Sex Med        ISSN: 1743-6095            Impact factor:   3.802


  10 in total

1.  The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function.

Authors:  R Rosen; C Brown; J Heiman; S Leiblum; C Meston; R Shabsigh; D Ferguson; R D'Agostino
Journal:  J Sex Marital Ther       Date:  2000 Apr-Jun

2.  Simple strategies for vaginal health promotion in cancer survivors.

Authors:  Jeanne Carter; Deborah Goldfrank; Leslie R Schover
Journal:  J Sex Med       Date:  2010-08-16       Impact factor: 3.802

3.  Baseline characteristics and concerns of female cancer patients/survivors seeking treatment at a Female Sexual Medicine Program.

Authors:  Jeanne Carter; Cara Stabile; Barbara Seidel; Raymond E Baser; Abigail R Gunn; Stephanie Chi; Rebecca F Steed; Shari Goldfarb; Deborah J Goldfrank
Journal:  Support Care Cancer       Date:  2015-01-08       Impact factor: 3.603

4.  Comparative patient-centered outcomes (health state and adverse sexual symptoms) between adjuvant brachytherapy versus no adjuvant brachytherapy in early stage endometrial cancer.

Authors:  Shari Damast; Kaled Alektiar; Anne Eaton; Naamit Kurshan Gerber; Shari Goldfarb; Sujata Patil; Rachel Jia; Mario Leitao; Jeanne Carter; Ethan Basch
Journal:  Ann Surg Oncol       Date:  2014-03-12       Impact factor: 5.344

5.  Psychometric validation of the Female Sexual Function Index (FSFI) in cancer survivors.

Authors:  Raymond E Baser; Yuelin Li; Jeanne Carter
Journal:  Cancer       Date:  2012-02-22       Impact factor: 6.860

6.  The comparison of hyaluronic acid vaginal tablets with estradiol vaginal tablets in the treatment of atrophic vaginitis: a randomized controlled trial.

Authors:  Murat Ekin; Levent Yaşar; Kadir Savan; Muzaffer Temur; Mehmet Uhri; Işıl Gencer; Esra Kıvanç
Journal:  Arch Gynecol Obstet       Date:  2010-02-05       Impact factor: 2.344

7.  Adjuvant exemestane with ovarian suppression in premenopausal breast cancer.

Authors:  Olivia Pagani; Meredith M Regan; Barbara A Walley; Gini F Fleming; Marco Colleoni; István Láng; Henry L Gomez; Carlo Tondini; Harold J Burstein; Edith A Perez; Eva Ciruelos; Vered Stearns; Hervé R Bonnefoi; Silvana Martino; Charles E Geyer; Graziella Pinotti; Fabio Puglisi; Diana Crivellari; Thomas Ruhstaller; Eric P Winer; Manuela Rabaglio-Poretti; Rudolf Maibach; Barbara Ruepp; Anita Giobbie-Hurder; Karen N Price; Jürg Bernhard; Weixiu Luo; Karin Ribi; Giuseppe Viale; Alan S Coates; Richard D Gelber; Aron Goldhirsch; Prudence A Francis
Journal:  N Engl J Med       Date:  2014-06-01       Impact factor: 91.245

8.  Impact of vulvovaginal health on postmenopausal women: a review of surveys on symptoms of vulvovaginal atrophy.

Authors:  Sharon J Parish; Rossella E Nappi; Michael L Krychman; Susan Kellogg-Spadt; James A Simon; Jeffrey A Goldstein; Sheryl A Kingsberg
Journal:  Int J Womens Health       Date:  2013-07-29

9.  Vulvar and vaginal atrophy in four European countries: evidence from the European REVIVE Survey.

Authors:  R E Nappi; S Palacios; N Panay; M Particco; M L Krychman
Journal:  Climacteric       Date:  2015-11-19       Impact factor: 3.005

Review 10.  Treating vulvovaginal atrophy/genitourinary syndrome of menopause: how important is vaginal lubricant and moisturizer composition?

Authors:  D Edwards; N Panay
Journal:  Climacteric       Date:  2015-12-26       Impact factor: 3.005

  10 in total
  5 in total

1.  A single-arm clinical trial investigating the effectiveness of a non-hormonal, hyaluronic acid-based vaginal moisturizer in endometrial cancer survivors.

Authors:  Jeanne Carter; Shari Goldfarb; Raymond E Baser; Deborah J Goldfrank; Barbara Seidel; Lisania Milli; Sally Saban; Cara Stabile; Jocelyn Canty; Ginger J Gardner; Elizabeth L Jewell; Yukio Sonoda; Marisa A Kollmeier; Kaled M Alektiar
Journal:  Gynecol Oncol       Date:  2020-06-08       Impact factor: 5.482

2.  Correspondence Between Clinician Ratings of Vulvovaginal Health and Patient-Reported Sexual Function After Cancer.

Authors:  Kathryn E Flynn; Li Lin; Jeanne Carter; Raymond E Baser; Shari Goldfarb; Sally Saban; Kevin P Weinfurt
Journal:  J Sex Med       Date:  2021-08-24       Impact factor: 3.937

3.  Pilot study of fractional CO2 laser therapy for genitourinary syndrome of menopause in gynecologic cancer survivors.

Authors:  Allison M Quick; Travis Dockter; Jennifer Le-Rademacher; Ritu Salani; Catherine Hudson; Andrew Hundley; Shelby Terstriep; Lauren Streicher; Stephanie Faubion; Charles L Loprinzi; Jenell S Coleman; Karen C Wang; Maryam Lustberg
Journal:  Maturitas       Date:  2020-12-02       Impact factor: 4.342

4.  Long-Term Follow-Up of Fractional CO2 Laser Therapy for Genitourinary Syndrome of Menopause in Breast Cancer Survivors.

Authors:  Allison M Quick; Andrew Hundley; Cynthia Evans; Julie A Stephens; Bhuvaneswari Ramaswamy; Raquel E Reinbolt; Anne M Noonan; Jeffrey Bryan Van Deusen; Robert Wesolowski; Daniel G Stover; Nicole Olivia Williams; Sagar D Sardesai; Stephanie S Faubion; Charles L Loprinzi; Maryam B Lustberg
Journal:  J Clin Med       Date:  2022-01-31       Impact factor: 4.241

5.  A pilot randomized controlled trial of vaginal estrogen on postpartum atrophy, perineal pain, and sexual function.

Authors:  Pamela E Smith; Eric M McLaughlin; Lopa K Pandya; Erinn M Hade; Courtney D Lynch; Catherine O Hudson
Journal:  Int Urogynecol J       Date:  2022-04-20       Impact factor: 1.932

  5 in total

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